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Zinc ： Acne

A

A meta-analysis found zinc supplementation (30-45 mg/day for 8-12 weeks) significantly reduced inflammatory acne lesions. Zinc inhibits 5-alpha-reductase, C. acnes growth, and inflammatory cytokines.

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            A

        

        

            
結論

            
            
A meta-analysis found zinc supplementation (30-45 mg/day for 8-12 weeks) significantly reduced inflammatory acne lesions. Zinc inhibits 5-alpha-reductase, C. acnes growth, and inflammatory cytokines.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
12

        
研究数

    

    

        
900

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        A

        
グレード

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
8-11 mg/day (RDA)

                    

                    
                    

                        
acneskinhealth:

                        
15-30 mg/day

                    

                    
                

                
                

                    上限量： 40 mg/day (elemental zinc — higher doses may cause copper depletion)
                

                
            

            

            

            
            

                推奨摂取タイミング： With meals to reduce nausea; avoid taking with iron or calcium
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Nausea (especially on empty stomach)
                        
    • 
                        
                        
  • 
                            ⚠
                            Copper depletion with long-term high-dose use
                        
    • 
                        
                        
  • 
                            ⚠
                            Metallic taste
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Copper supplements (mutual absorption competition — separate by 2+ hours)
                        
    • 
                        
                        
  • 
                            ●
                            Tetracycline and quinolone antibiotics (reduced antibiotic absorption)
                        
    • 
                        
                        
  • 
                            ●
                            Penicillamine (reduced absorption of both)
                        
    • 
                        
                        
  • 
                            ●
                            Iron supplements (competitive absorption)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： 40 mg/day (elemental zinc — higher doses may cause copper depletion)
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Zinc help with Acne?
            
        
        

            Based on 12 studies with 900 participants, there is strong evidence from multiple clinical trials that Zinc may support Acne management. Our evidence grade is A (Strong Evidence).
        

    

    
    

        
            How much Zinc should I take for Acne?
            
        
        

            Studies have used various dosages. A commonly studied range is 8-11 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Zinc?
            
        
        

            Reported side effects may include Nausea (especially on empty stomach), Copper depletion with long-term high-dose use, Metallic taste, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Zinc and Acne?
            
        
        

            We rate the evidence as Grade A (Strong Evidence). This rating is based on 12 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Zinc 他の症状・状態について

                    

                        
                        
                            Wound Healing
                            A

                        
                        
                    

                

                
            

        

        

    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。