Zinc 관련 여드름
A 근거 여러 대규모 임상 시험이 일관되게 유의미한 효과를 보여줍니다.A meta-analysis found zinc supplementation (30-45 mg/day for 8-12 weeks) significantly reduced inflammatory acne lesions. Zinc inhibits 5-alpha-reductase, C. acnes growth, and inflammatory cytokines.
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A
결론
A meta-analysis found zinc supplementation (30-45 mg/day for 8-12 weeks) significantly reduced inflammatory acne lesions. Zinc inhibits 5-alpha-reductase, C. acnes growth, and inflammatory cytokines.
Key Study Findings
Review
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Dose: None
vs: Placebo
효과: None
None
Review
The role of trace elements for the function and health of the skin.
Dose: None
vs: Placebo
효과: None
None
Review
Possible relationship between poor skin disorders prognosis and serum zinc level: A narrative review.
Dose: None
vs: Placebo
효과: None
None
Case-control
n=76
Histone deacetylase 1 in patients with alopecia areata and acne vulgaris: An epigenetic alteration.
Dose: None
vs: Placebo
효과: None
p=0.0001
narrative_review
Nutrition and skin: Kids are not just little people.
Dose: None
vs: Placebo
효과: narrative review; discusses role of nutrition from prenatal period on skin immune responses; highlig
not_applicable
Case Reports
n=1
26 weeks
Excessive oral zinc supplementation.
Dose: Large daily doses of zinc supplements
vs: None
Outcome: Zinc-induced copper deficiency
효과: Developed anemia, leukopenia from hypocupremia
None
대상 집단: 17-year-old boy self-treating acne with excess zinc
Key Statistics
12
연구
900
참여자
↑
Positive
A
등급
Referenced Papers
Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.
Review
Current medicinal chemistry
2025
5 인용
Journal of trace …
2025
4 인용
Dermatology reports
2022
4 인용
Histone deacetylase 1 in patients with alopecia areata and acne vulgaris: An epigenetic alteration.
Other
The Australasian journal …
2022
4 인용
Annales de dermatologie …
2021
4 인용
Clinics in dermatology
2016
19 인용
American journal of …
2005
140 인용
Excessive oral zinc supplementation.
Case Report
Journal of pediatric …
2002
80 인용
Annales Universitatis Mariae …
1990
Zeitschrift fur Hautkrankheiten
1987
3 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 8-11 mg/day (RDA)
- acneskinhealth:
- 15-30 mg/day
상한량: 40 mg/day (elemental zinc — higher doses may cause copper depletion)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Negative | -- |
| None | -- | Negative | 76 |
| None | -- | Positive | -- |
| Large daily doses of zinc supplements | 26 weeks | Negative | 1 |
| 2 g | -- | Mixed | -- |
| None | -- | Positive | -- |
권장 복용 시간: With meals to reduce nausea; avoid taking with iron or calcium
Safety & Side Effects
보고된 부작용
- ⚠ Nausea (especially on empty stomach)
- ⚠ Copper depletion with long-term high-dose use
- ⚠ Metallic taste
- ⚠ Headache
알려진 상호작용
- ● Copper supplements (mutual absorption competition — separate by 2+ hours)
- ● Tetracycline and quinolone antibiotics (reduced antibiotic absorption)
- ● Penicillamine (reduced absorption of both)
- ● Iron supplements (competitive absorption)
일일 최대 섭취 허용량: 40 mg/day (elemental zinc — higher doses may cause copper depletion)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Zinc help with 여드름?
Based on 12 studies with 900 participants, there is strong evidence from multiple clinical trials that Zinc may support 여드름 management. Our evidence grade is A (Strong Evidence).
How much Zinc should I take for 여드름?
Studies have used various dosages. A commonly studied range is 8-11 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Zinc?
Reported side effects may include Nausea (especially on empty stomach), Copper depletion with long-term high-dose use, Metallic taste, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Zinc and 여드름?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 12 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: 여드름
Zinc 다른 건강 상태에 대한 근거
References
- [1] Geir Bjørklund et al.. Curr Med Chem. 2025. Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders. doi:10.2174/0109298673348175250214054101 PubMed
- [2] Geir Bjørklund et al.. J Trace Elem Med Biol. 2025. The role of trace elements for the function and health of the skin. doi:10.1016/j.jtemb.2025.127674 PubMed
- [3] Mohammed Al Abadie et al.. Dermatol Reports. 2022. Possible relationship between poor skin disorders prognosis and serum zinc level: A narrative review. doi:10.4081/dr.2022.9512 PubMed
- [4] Heba Ahmed Abdelkader et al.. Australas J Dermatol. 2022. Histone deacetylase 1 in patients with alopecia areata and acne vulgaris: An epigenetic alteration. doi:10.1111/ajd.13784 PubMed
- [5] F Poizeau et al.. Ann Dermatol Venereol. 2021. Vulvar Fordyce adenitis: A cohort of 45 women. doi:10.1016/j.annder.2021.04.001 PubMed
- [6] Meagen McCusker et al.. Clin Dermatol. 2016. Nutrition and skin: Kids are not just little people. doi:10.1016/j.clindermatol.2016.07.004 PubMed
- [7] Renata Strumia. Am J Clin Dermatol. 2005. Dermatologic signs in patients with eating disorders. doi:10.2165/00128071-200506030-00003 PubMed
- [8] Mark B Salzman et al.. J Pediatr Hematol Oncol. 2002. Excessive oral zinc supplementation. doi:10.1097/00043426-200210000-00020 PubMed
- [9] G Chodorowska et al.. Ann Univ Mariae Curie Sklodowska Med. 1990. [Study of the zinc content of hair and serum in selected skin diseases]. PubMed
- [10] F Leyh. Z Hautkr. 1987. [Zinc--a new therapeutic principle in dermatology?]. PubMed
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.