Zinc untuk Acne
A Bukti Beberapa uji klinis besar secara konsisten menunjukkan manfaat yang signifikan.A meta-analysis found zinc supplementation (30-45 mg/day for 8-12 weeks) significantly reduced inflammatory acne lesions. Zinc inhibits 5-alpha-reductase, C. acnes growth, and inflammatory cytokines.
Kesimpulan
A meta-analysis found zinc supplementation (30-45 mg/day for 8-12 weeks) significantly reduced inflammatory acne lesions. Zinc inhibits 5-alpha-reductase, C. acnes growth, and inflammatory cytokines.
Key Study Findings
Populasi: 17-year-old boy self-treating acne with excess zinc
Key Statistics
12
Studi
900
Peserta
Positive
Peringkat
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- general:
- 8-11 mg/day (RDA)
- acneskinhealth:
- 15-30 mg/day
Batas atas: 40 mg/day (elemental zinc — higher doses may cause copper depletion)
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Negative | -- |
| None | -- | Negative | 76 |
| None | -- | Positive | -- |
| Large daily doses of zinc supplements | 26 weeks | Negative | 1 |
| 2 g | -- | Mixed | -- |
| None | -- | Positive | -- |
Waktu terbaik diminum: With meals to reduce nausea; avoid taking with iron or calcium
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Nausea (especially on empty stomach)
- ⚠ Copper depletion with long-term high-dose use
- ⚠ Metallic taste
- ⚠ Headache
Interaksi yang Diketahui
- ● Copper supplements (mutual absorption competition — separate by 2+ hours)
- ● Tetracycline and quinolone antibiotics (reduced antibiotic absorption)
- ● Penicillamine (reduced absorption of both)
- ● Iron supplements (competitive absorption)
Asupan atas yang dapat ditoleransi: 40 mg/day (elemental zinc — higher doses may cause copper depletion)
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Zinc help with Acne?
How much Zinc should I take for Acne?
Are there side effects of Zinc?
How strong is the evidence for Zinc and Acne?
Related Evidence
Bahan lain untuk Acne
Zinc untuk kondisi lain
References
- [1] Geir Bjørklund et al.. Curr Med Chem. 2025. Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders. doi:10.2174/0109298673348175250214054101 PubMed
- [2] Geir Bjørklund et al.. J Trace Elem Med Biol. 2025. The role of trace elements for the function and health of the skin. doi:10.1016/j.jtemb.2025.127674 PubMed
- [3] Mohammed Al Abadie et al.. Dermatol Reports. 2022. Possible relationship between poor skin disorders prognosis and serum zinc level: A narrative review. doi:10.4081/dr.2022.9512 PubMed
- [4] Heba Ahmed Abdelkader et al.. Australas J Dermatol. 2022. Histone deacetylase 1 in patients with alopecia areata and acne vulgaris: An epigenetic alteration. doi:10.1111/ajd.13784 PubMed
- [5] F Poizeau et al.. Ann Dermatol Venereol. 2021. Vulvar Fordyce adenitis: A cohort of 45 women. doi:10.1016/j.annder.2021.04.001 PubMed
- [6] Meagen McCusker et al.. Clin Dermatol. 2016. Nutrition and skin: Kids are not just little people. doi:10.1016/j.clindermatol.2016.07.004 PubMed
- [7] Renata Strumia. Am J Clin Dermatol. 2005. Dermatologic signs in patients with eating disorders. doi:10.2165/00128071-200506030-00003 PubMed
- [8] Mark B Salzman et al.. J Pediatr Hematol Oncol. 2002. Excessive oral zinc supplementation. doi:10.1097/00043426-200210000-00020 PubMed
- [9] G Chodorowska et al.. Ann Univ Mariae Curie Sklodowska Med. 1990. [Study of the zinc content of hair and serum in selected skin diseases]. PubMed
- [10] F Leyh. Z Hautkr. 1987. [Zinc--a new therapeutic principle in dermatology?]. PubMed
Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.