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SkinCited

Resveratrol ： Aging Skin & Wrinkles

C

In vitro evidence is strong for anti-aging effects (SIRT1 activation, MMP inhibition). Oral bioavailability is extremely low (<2%), limiting clinical evidence for oral supplementation.

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            C

        

        

            
結論

            
            
In vitro evidence is strong for anti-aging effects (SIRT1 activation, MMP inhibition). Oral bioavailability is extremely low (<2%), limiting clinical evidence for oral supplementation.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
4

        
研究数

    

    

        
200

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
グレード

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
150-500 mg/day

                    

                    
                    

                        
skinhealth:

                        
250-500 mg/day trans-resveratrol

                    

                    
                

                
                

                    上限量： Generally well-tolerated up to 1,500 mg/day; GI discomfort above 2,500 mg/day
                

                
            

            

            

            
            

                推奨摂取タイミング： With meals for improved absorption; low oral bioavailability (~1-2%)
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Gastrointestinal discomfort at high doses
                        
    • 
                        
                        
  • 
                            ⚠
                            Diarrhea
                        
    • 
                        
                        
  • 
                            ⚠
                            May affect platelet aggregation
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (may have antiplatelet effects)
                        
    • 
                        
                        
  • 
                            ●
                            CYP450 substrates (may inhibit drug metabolism)
                        
    • 
                        
                        
  • 
                            ●
                            Estrogen-sensitive conditions (has weak estrogenic activity)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： Generally well-tolerated up to 1,500 mg/day; GI discomfort above 2,500 mg/day
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Resveratrol help with Aging Skin & Wrinkles?
            
        
        

            Based on 4 studies with 200 participants, there is limited but promising evidence that Resveratrol may support Aging Skin & Wrinkles management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Resveratrol should I take for Aging Skin & Wrinkles?
            
        
        

            Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Resveratrol?
            
        
        

            Reported side effects may include Gastrointestinal discomfort at high doses, Diarrhea, May affect platelet aggregation. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Resveratrol and Aging Skin & Wrinkles?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。