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SkinCited

Resveratrol
Resveratrol

antioxidant

别名: trans-Resveratrol, 3,5,4'-Trihydroxystilbene

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About





            

                
Resveratrol is a polyphenol stilbene that activates SIRT1 longevity pathways and inhibits tyrosinase to reduce melanogenesis. In vitro evidence is strong, but oral bioavailability is extremely low (< 2%). A small RCT found 250 mg/day for 60 days improved skin smoothness and reduced hyperpigmentation.

            

        

        

        
        
        

            

  
How It Works





            

                
Polyphenol stilbene that activates SIRT1 (sirtuin 1) longevity pathways; inhibits tyrosinase to reduce melanogenesis; suppresses NF-kB and COX-2 inflammatory cascades; may protect against UV-induced DNA damage and MMP expression.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Aging Skin & Wrinkles
                                    
                                
                                
                                    C

                                
                                
                                    4
                                
                                
                                    200
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Gastrointestinal discomfort at high doses
                
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                    Diarrhea
                
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                    May affect platelet aggregation
                
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Drug & Supplement Interactions





            
    
                
                
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                    Anticoagulants (may have antiplatelet effects)
                
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                    CYP450 substrates (may inhibit drug metabolism)
                
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                    Estrogen-sensitive conditions (has weak estrogenic activity)
                
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Related Ingredients





            

                
                
                    Astaxanthin
                    
                
                
                
                    Glutathione
                    
                
                
                
                    CoQ10
                    
                
                
                
                    Alpha-Lipoic Acid
                    
                
                
            

        

        
    


    
    












    

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