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Evening Primrose Oil 用于 湿疹（特应性皮炎）

C 证据 来自小型研究的证据有限，但存在一些积极信号。

Mixed results in systematic reviews. Some individual RCTs show improvement in eczema itch and dryness, but Cochrane review found insufficient overall evidence. May benefit those with delta-6-desaturase deficiency.

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            C

        

        

            
结论

            
            
Mixed results in systematic reviews. Some individual RCTs show improvement in eczema itch and dryness, but Cochrane review found insufficient overall evidence. May benefit those with delta-6-desaturase deficiency.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Systematic Review
                
                
                
                
            

            
                Dietary supplements for established atopic eczema.
            
            

                
                Dose: None
                
                
                vs: Placebo
                
                
                Outcome: Atopic eczema severity
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: Adults and children with established atopic eczema

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
12

        
研究数量

    

    

        
800

        
受试者

    

    

        
            
            ↔
            
        
        
Mixed

    

    

        C

        
等级

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Dietary supplements for established atopic eczema.
                        
                        
                            
                                Meta-Analysis
                            
                            
                            
                        
                    

                    

                        The Cochrane database …
                        2012
                        
                        130 次引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
500-1,000 mg/day

                    

                    
                    

                        
eczemaskinhealth:

                        
1,000-3,000 mg/day (providing 80-300 mg GLA)

                    

                    
                

                
                

                    上限： Not established; generally well-tolerated up to 6,000 mg/day
                

                
            

            

            
            

                
研究中使用的剂量

                

                    

                        
                            

                                剂量
                                持续时间
                                效果
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Neutral
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                最佳服用时间： With meals for better absorption
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            May lower seizure threshold (theoretical)
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (may have mild antiplatelet effects)
                        
    • 
                        
                        
  • 
                            ●
                            Phenothiazines and anticonvulsants (may lower seizure threshold)
                        
    • 
                        
                        
  • 
                            ●
                            NSAIDs (may have additive GI effects)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： Not established; generally well-tolerated up to 6,000 mg/day
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Evening Primrose Oil help with 湿疹（特应性皮炎）?
            
        
        

            Based on 12 studies with 800 participants, there is limited but promising evidence that Evening Primrose Oil may support 湿疹（特应性皮炎） management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Evening Primrose Oil should I take for 湿疹（特应性皮炎）?
            
        
        

            Studies have used various dosages. A commonly studied range is 500-1,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Evening Primrose Oil?
            
        
        

            Reported side effects may include Mild gastrointestinal discomfort, Headache (rare), May lower seizure threshold (theoretical). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Evening Primrose Oil and 湿疹（特应性皮炎）?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 12 peer-reviewed studies with 800 total participants. The overall direction of effect is mixed.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Fiona J Bath-Hextall et al..
      Cochrane Database Syst Rev.
      2012.
      Dietary supplements for established atopic eczema.
      doi:10.1002/14651858.CD005205.pub3
      PubMed
    
    2. 
    
  















    

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