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Borage Oil 用于 湿疹（特应性皮炎）

C 证据 来自小型研究的证据有限，但存在一些积极信号。

Contains 2x more GLA than EPO. Some RCTs showed improved skin barrier function and reduced TEWL in atopic dermatitis. Cochrane review findings are mixed for GLA oils overall.

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            C

        

        

            
结论

            
            
Contains 2x more GLA than EPO. Some RCTs showed improved skin barrier function and reduced TEWL in atopic dermatitis. Cochrane review findings are mixed for GLA oils overall.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Systematic Review
                
                
                
                
            

            
                Dietary supplements for established atopic eczema.
            
            

                
                Dose: None
                
                
                vs: Placebo
                
                
                Outcome: Atopic eczema severity
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: Adults and children with established atopic eczema

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
8

        
研究数量

    

    

        
500

        
受试者

    

    

        
            
            ↔
            
        
        
Mixed

    

    

        C

        
等级

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Dietary supplements for established atopic eczema.
                        
                        
                            
                                Meta-Analysis
                            
                            
                            
                        
                    

                    

                        The Cochrane database …
                        2012
                        
                        130 次引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
500-1,000 mg/day

                    

                    
                    

                        
skinhealth:

                        
1,000-2,000 mg/day (providing 200-500 mg GLA)

                    

                    
                

                
                

                    上限： Not established; generally well-tolerated
                

                
            

            

            
            

                
研究中使用的剂量

                

                    

                        
                            

                                剂量
                                持续时间
                                效果
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Neutral
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                最佳服用时间： With meals
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Soft stools
                        
    • 
                        
                        
  • 
                            ⚠
                            Possible hepatotoxicity with PA-containing preparations (use PA-free only)
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (may have antiplatelet effects)
                        
    • 
                        
                        
  • 
                            ●
                            Anticonvulsants (theoretical seizure threshold concern)
                        
    • 
                        
                        
  • 
                            ●
                            Hepatotoxic medications (PA content concern — use PA-free)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： Not established; generally well-tolerated
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Borage Oil help with 湿疹（特应性皮炎）?
            
        
        

            Based on 8 studies with 500 participants, there is limited but promising evidence that Borage Oil may support 湿疹（特应性皮炎） management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Borage Oil should I take for 湿疹（特应性皮炎）?
            
        
        

            Studies have used various dosages. A commonly studied range is 500-1,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Borage Oil?
            
        
        

            Reported side effects may include Mild gastrointestinal discomfort, Soft stools, Possible hepatotoxicity with PA-containing preparations (use PA-free only). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Borage Oil and 湿疹（特应性皮炎）?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 8 peer-reviewed studies with 500 total participants. The overall direction of effect is mixed.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Fiona J Bath-Hextall et al..
      Cochrane Database Syst Rev.
      2012.
      Dietary supplements for established atopic eczema.
      doi:10.1002/14651858.CD005205.pub3
      PubMed
    
    2. 
    
  















    

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