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Biotin 用于 皮肤干燥

D 研究 目前仅存在初步研究(实验室研究、病例报告)。

Biotin supports fatty acid synthesis in the stratum corneum. Deficiency causes dry skin, but evidence for supplementation in non-deficient individuals is limited.

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D

结论

Biotin supports fatty acid synthesis in the stratum corneum. Deficiency causes dry skin, but evidence for supplementation in non-deficient individuals is limited.

Key Study Findings

review
Advanced Applications of Vitamin B Complex in Plastic and Cosmetic Surgery: Mechanisms and Therapeutic Benefits.
Dose: Vitamin B complex (various B vitamins including niacinamide/NAD+ precursor) vs: Placebo 效果: None None
laboratory/in vitro 26 weeks
Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line.
Dose: F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. vs: Placebo 效果: F1 and F3 stable for 180 days; F2 stable for 14 days; F4 and F5 stable for 150 days; F6/F7 stable fo None
Review
Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why.
Dose: 14 nutritional compounds (vitamins, minerals, etc.) vs: None Outcome: Skin health and barrier function 效果: None None

研究人群: General population (skin health review)

cross-sectional survey n=144
Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey among …
Dose: None vs: Placebo 效果: None None

Key Statistics

2

研究数量

100

受试者

Positive

D

等级

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:
30 mcg/day (AI)
skinhairnails:
2,500-5,000 mcg/day

上限: No established UL (water-soluble); may interfere with lab tests at high doses

研究中使用的剂量

剂量 持续时间 效果 N
Vitamin B complex (various B vitamins including niacinamide/NAD+ precursor) -- Positive --
F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. 26 weeks Positive --
not applicable -- Mixed 180
14 nutritional compounds (vitamins, minerals, etc.) -- Positive --
None -- Mixed --
None -- Neutral 144

最佳服用时间: With meals for better absorption

Safety & Side Effects

已报告的副作用

  • Generally well-tolerated
  • May cause acne breakouts at high doses (> 5,000 mcg)
  • Interferes with troponin and thyroid laboratory tests

已知相互作用

  • Laboratory test interference (troponin, thyroid panels, vitamin D assays)
  • Anticonvulsants (carbamazepine, phenytoin may reduce biotin levels)
  • Prolonged antibiotic use (may reduce gut biotin synthesis)

可耐受最高摄入量: No established UL (water-soluble); may interfere with lab tests at high doses

在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Biotin help with 皮肤干燥?
Based on 2 studies with 100 participants, there is preliminary evidence that needs more research that Biotin may support 皮肤干燥 management. Our evidence grade is D (Very Early Research).
How much Biotin should I take for 皮肤干燥?
Studies have used various dosages. A commonly studied range is 30 mcg/day (AI). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Biotin?
Reported side effects may include Generally well-tolerated, May cause acne breakouts at high doses (> 5,000 mcg), Interferes with troponin and thyroid laboratory tests. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Biotin and 皮肤干燥?
We rate the evidence as Grade D (Very Early Research). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

References

  1. [1] Carolina Schettino Kegele et al.. Int J Pharm Compd. 2025. Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line. PubMed
  2. [2] Feiya Du et al.. Int J Vitam Nutr Res. 2025. Advanced Applications of Vitamin B Complex in Plastic and Cosmetic Surgery: Mechanisms and Therapeutic Benefits. doi:10.31083/IJVNR39087 PubMed
  3. [3] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
  4. [4] Jacek Januszewski et al.. Medicina (Kaunas). 2023. Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why. doi:10.3390/medicina60010068 PubMed
  5. [5] Katherine G Thompson et al.. J Am Acad Dermatol. 2021. Dietary supplements in dermatology: A review of the evidence for zinc, biotin, vitamin D, nicotinamide, and Polypodium. doi:10.1016/j.jaad.2020.04.123 PubMed
  6. [6] Thomas Hengl et al.. J Photochem Photobiol B. 2018. Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. doi:10.1016/j.jphotobiol.2018.09.005 PubMed
  7. [7] Ralph M Trüeb. Int J Trichology. 2016. Serum Biotin Levels in Women Complaining of Hair Loss. doi:10.4103/0974-7753.188040 PubMed
  8. [8] Thamer Mubki. J Cutan Med Surg. 2014. Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey among Dermatologists in Saudi Arabia. doi:10.2310/7750.2014.14008 PubMed
  9. [9] Michael W Cashman et al.. Clin Dermatol. 2010. Nutrition and nail disease. doi:10.1016/j.clindermatol.2010.03.037 PubMed

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