Biotin 用于 皮肤干燥
D 研究 目前仅存在初步研究(实验室研究、病例报告)。Biotin supports fatty acid synthesis in the stratum corneum. Deficiency causes dry skin, but evidence for supplementation in non-deficient individuals is limited.
结论
Biotin supports fatty acid synthesis in the stratum corneum. Deficiency causes dry skin, but evidence for supplementation in non-deficient individuals is limited.
Key Study Findings
研究人群: General population (skin health review)
Key Statistics
2
研究数量
100
受试者
Positive
等级
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 30 mcg/day (AI)
- skinhairnails:
- 2,500-5,000 mcg/day
上限: No established UL (water-soluble); may interfere with lab tests at high doses
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| Vitamin B complex (various B vitamins including niacinamide/NAD+ precursor) | -- | Positive | -- |
| F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. | 26 weeks | Positive | -- |
| not applicable | -- | Mixed | 180 |
| 14 nutritional compounds (vitamins, minerals, etc.) | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | 144 |
最佳服用时间: With meals for better absorption
Safety & Side Effects
已报告的副作用
- ⚠ Generally well-tolerated
- ⚠ May cause acne breakouts at high doses (> 5,000 mcg)
- ⚠ Interferes with troponin and thyroid laboratory tests
已知相互作用
- ● Laboratory test interference (troponin, thyroid panels, vitamin D assays)
- ● Anticonvulsants (carbamazepine, phenytoin may reduce biotin levels)
- ● Prolonged antibiotic use (may reduce gut biotin synthesis)
可耐受最高摄入量: No established UL (water-soluble); may interfere with lab tests at high doses
在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Biotin help with 皮肤干燥?
How much Biotin should I take for 皮肤干燥?
Are there side effects of Biotin?
How strong is the evidence for Biotin and 皮肤干燥?
Related Evidence
Biotin 用于其他健康状况
References
- [1] Carolina Schettino Kegele et al.. Int J Pharm Compd. 2025. Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line. PubMed
- [2] Feiya Du et al.. Int J Vitam Nutr Res. 2025. Advanced Applications of Vitamin B Complex in Plastic and Cosmetic Surgery: Mechanisms and Therapeutic Benefits. doi:10.31083/IJVNR39087 PubMed
- [3] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
- [4] Jacek Januszewski et al.. Medicina (Kaunas). 2023. Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why. doi:10.3390/medicina60010068 PubMed
- [5] Katherine G Thompson et al.. J Am Acad Dermatol. 2021. Dietary supplements in dermatology: A review of the evidence for zinc, biotin, vitamin D, nicotinamide, and Polypodium. doi:10.1016/j.jaad.2020.04.123 PubMed
- [6] Thomas Hengl et al.. J Photochem Photobiol B. 2018. Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. doi:10.1016/j.jphotobiol.2018.09.005 PubMed
- [7] Ralph M Trüeb. Int J Trichology. 2016. Serum Biotin Levels in Women Complaining of Hair Loss. doi:10.4103/0974-7753.188040 PubMed
- [8] Thamer Mubki. J Cutan Med Surg. 2014. Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey among Dermatologists in Saudi Arabia. doi:10.2310/7750.2014.14008 PubMed
- [9] Michael W Cashman et al.. Clin Dermatol. 2010. Nutrition and nail disease. doi:10.1016/j.clindermatol.2010.03.037 PubMed
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