Biotin ： Dry Skin
D 研究 予備的な研究（実験室研究、症例報告）のみが存在します。Biotin supports fatty acid synthesis in the stratum corneum. Deficiency causes dry skin, but evidence for supplementation in non-deficient individuals is limited.
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D
結論
Biotin supports fatty acid synthesis in the stratum corneum. Deficiency causes dry skin, but evidence for supplementation in non-deficient individuals is limited.
Key Study Findings
review
Advanced Applications of Vitamin B Complex in Plastic and Cosmetic Surgery: Mechanisms and Therapeutic Benefits.
Dose: Vitamin B complex (various B vitamins including niacinamide/NAD+ precursor)
vs: Placebo
効果: None
None
laboratory/in vitro
26 weeks
Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line.
Dose: F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0.
vs: Placebo
効果: F1 and F3 stable for 180 days; F2 stable for 14 days; F4 and F5 stable for 150 days; F6/F7 stable fo
None
case-control study
n=180
A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, …
Dose: not applicable
vs: Placebo
効果: None
None
Review
Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why.
Dose: 14 nutritional compounds (vitamins, minerals, etc.)
vs: None
Outcome: Skin health and barrier function
効果: None
None
対象集団: General population (skin health review)
Review
Dietary supplements in dermatology: A review of the evidence for zinc, biotin, vitamin D, nicotinamide, …
Dose: None
vs: Placebo
効果: None
None
cross-sectional survey
n=144
Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey among …
Dose: None
vs: Placebo
効果: None
None
Key Statistics
2
研究数
100
参加者数
↑
Positive
D
グレード
Referenced Papers
International journal of …
2025
International journal for …
2025
Journal of cosmetic …
2024
7 件の引用
Medicina (Kaunas, Lithuania)
2023
41 件の引用
Journal of the …
2021
46 件の引用
Journal of photochemistry …
2018
16 件の引用
International journal of …
2016
89 件の引用
Journal of cutaneous …
2014
10 件の引用
Clinics in dermatology
2010
98 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 30 mcg/day (AI)
- skinhairnails:
- 2,500-5,000 mcg/day
上限量： No established UL (water-soluble); may interfere with lab tests at high doses
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| Vitamin B complex (various B vitamins including niacinamide/NAD+ precursor) | -- | Positive | -- |
| F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. | 26 weeks | Positive | -- |
| not applicable | -- | Mixed | 180 |
| 14 nutritional compounds (vitamins, minerals, etc.) | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | 144 |
推奨摂取タイミング： With meals for better absorption
Safety & Side Effects
報告されている副作用
- ⚠ Generally well-tolerated
- ⚠ May cause acne breakouts at high doses (> 5,000 mcg)
- ⚠ Interferes with troponin and thyroid laboratory tests
既知の相互作用
- ● Laboratory test interference (troponin, thyroid panels, vitamin D assays)
- ● Anticonvulsants (carbamazepine, phenytoin may reduce biotin levels)
- ● Prolonged antibiotic use (may reduce gut biotin synthesis)
耐容上限摂取量： No established UL (water-soluble); may interfere with lab tests at high doses
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does Biotin help with Dry Skin?
Based on 2 studies with 100 participants, there is preliminary evidence that needs more research that Biotin may support Dry Skin management. Our evidence grade is D (Very Early Research).
How much Biotin should I take for Dry Skin?
Studies have used various dosages. A commonly studied range is 30 mcg/day (AI). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Biotin?
Reported side effects may include Generally well-tolerated, May cause acne breakouts at high doses (> 5,000 mcg), Interferes with troponin and thyroid laboratory tests. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Biotin and Dry Skin?
We rate the evidence as Grade D (Very Early Research). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
Related Evidence
に関する他の成分： Dry Skin
Biotin 他の症状・状態について
References
- [1] Carolina Schettino Kegele et al.. Int J Pharm Compd. 2025. Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line. PubMed
- [2] Feiya Du et al.. Int J Vitam Nutr Res. 2025. Advanced Applications of Vitamin B Complex in Plastic and Cosmetic Surgery: Mechanisms and Therapeutic Benefits. doi:10.31083/IJVNR39087 PubMed
- [3] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
- [4] Jacek Januszewski et al.. Medicina (Kaunas). 2023. Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why. doi:10.3390/medicina60010068 PubMed
- [5] Katherine G Thompson et al.. J Am Acad Dermatol. 2021. Dietary supplements in dermatology: A review of the evidence for zinc, biotin, vitamin D, nicotinamide, and Polypodium. doi:10.1016/j.jaad.2020.04.123 PubMed
- [6] Thomas Hengl et al.. J Photochem Photobiol B. 2018. Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. doi:10.1016/j.jphotobiol.2018.09.005 PubMed
- [7] Ralph M Trüeb. Int J Trichology. 2016. Serum Biotin Levels in Women Complaining of Hair Loss. doi:10.4103/0974-7753.188040 PubMed
- [8] Thamer Mubki. J Cutan Med Surg. 2014. Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey among Dermatologists in Saudi Arabia. doi:10.2310/7750.2014.14008 PubMed
- [9] Michael W Cashman et al.. Clin Dermatol. 2010. Nutrition and nail disease. doi:10.1016/j.clindermatol.2010.03.037 PubMed
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