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Biotin untuk Dry Skin

D Penelitian Hanya penelitian awal yang ada (studi laboratorium, laporan kasus).

Biotin supports fatty acid synthesis in the stratum corneum. Deficiency causes dry skin, but evidence for supplementation in non-deficient individuals is limited.

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D

Kesimpulan

Biotin supports fatty acid synthesis in the stratum corneum. Deficiency causes dry skin, but evidence for supplementation in non-deficient individuals is limited.

Key Study Findings

review
Advanced Applications of Vitamin B Complex in Plastic and Cosmetic Surgery: Mechanisms and Therapeutic Benefits.
Dose: Vitamin B complex (various B vitamins including niacinamide/NAD+ precursor) vs: Placebo Efek: None None
laboratory/in vitro 26 weeks
Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line.
Dose: F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. vs: Placebo Efek: F1 and F3 stable for 180 days; F2 stable for 14 days; F4 and F5 stable for 150 days; F6/F7 stable fo None
Review
Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why.
Dose: 14 nutritional compounds (vitamins, minerals, etc.) vs: None Outcome: Skin health and barrier function Efek: None None

Populasi: General population (skin health review)

cross-sectional survey n=144
Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey among …
Dose: None vs: Placebo Efek: None None

Key Statistics

2

Studi

100

Peserta

Positive

D

Peringkat

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
30 mcg/day (AI)
skinhairnails:
2,500-5,000 mcg/day

Batas atas: No established UL (water-soluble); may interfere with lab tests at high doses

Dosis yang Diteliti dalam Penelitian

Dosis Durasi Efek N
Vitamin B complex (various B vitamins including niacinamide/NAD+ precursor) -- Positive --
F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. 26 weeks Positive --
not applicable -- Mixed 180
14 nutritional compounds (vitamins, minerals, etc.) -- Positive --
None -- Mixed --
None -- Neutral 144

Waktu terbaik diminum: With meals for better absorption

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Generally well-tolerated
  • May cause acne breakouts at high doses (> 5,000 mcg)
  • Interferes with troponin and thyroid laboratory tests

Interaksi yang Diketahui

  • Laboratory test interference (troponin, thyroid panels, vitamin D assays)
  • Anticonvulsants (carbamazepine, phenytoin may reduce biotin levels)
  • Prolonged antibiotic use (may reduce gut biotin synthesis)

Asupan atas yang dapat ditoleransi: No established UL (water-soluble); may interfere with lab tests at high doses

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Biotin help with Dry Skin?
Based on 2 studies with 100 participants, there is preliminary evidence that needs more research that Biotin may support Dry Skin management. Our evidence grade is D (Very Early Research).
How much Biotin should I take for Dry Skin?
Studies have used various dosages. A commonly studied range is 30 mcg/day (AI). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Biotin?
Reported side effects may include Generally well-tolerated, May cause acne breakouts at high doses (> 5,000 mcg), Interferes with troponin and thyroid laboratory tests. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Biotin and Dry Skin?
We rate the evidence as Grade D (Very Early Research). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

References

  1. [1] Carolina Schettino Kegele et al.. Int J Pharm Compd. 2025. Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line. PubMed
  2. [2] Feiya Du et al.. Int J Vitam Nutr Res. 2025. Advanced Applications of Vitamin B Complex in Plastic and Cosmetic Surgery: Mechanisms and Therapeutic Benefits. doi:10.31083/IJVNR39087 PubMed
  3. [3] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
  4. [4] Jacek Januszewski et al.. Medicina (Kaunas). 2023. Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why. doi:10.3390/medicina60010068 PubMed
  5. [5] Katherine G Thompson et al.. J Am Acad Dermatol. 2021. Dietary supplements in dermatology: A review of the evidence for zinc, biotin, vitamin D, nicotinamide, and Polypodium. doi:10.1016/j.jaad.2020.04.123 PubMed
  6. [6] Thomas Hengl et al.. J Photochem Photobiol B. 2018. Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. doi:10.1016/j.jphotobiol.2018.09.005 PubMed
  7. [7] Ralph M Trüeb. Int J Trichology. 2016. Serum Biotin Levels in Women Complaining of Hair Loss. doi:10.4103/0974-7753.188040 PubMed
  8. [8] Thamer Mubki. J Cutan Med Surg. 2014. Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey among Dermatologists in Saudi Arabia. doi:10.2310/7750.2014.14008 PubMed
  9. [9] Michael W Cashman et al.. Clin Dermatol. 2010. Nutrition and nail disease. doi:10.1016/j.clindermatol.2010.03.037 PubMed

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