What supplements have the most evidence for acne management?

Zinc (30 mg elemental daily), probiotics (L. rhamnosus GG), omega-3 fatty acids, and niacinamide have the most clinical evidence for acne improvement. Zinc has shown effects comparable to low-dose antibiotics in some trials. Pantothenic acid has emerging evidence. These supplements work best alongside standard dermatological treatments.

Can supplements alone clear acne?

Supplements alone are unlikely to fully resolve moderate to severe acne. Acne is influenced by hormones, sebum production, bacteria (C. acnes), and inflammation. Evidence-based treatments include topical retinoids, benzoyl peroxide, antibiotics, and for severe cases, isotretinoin. Supplements may provide modest adjunctive benefits alongside these treatments.

When should someone with acne see a dermatologist about supplements?

See a dermatologist if acne is moderate to severe, scarring, not responding to over-the-counter treatments after 8 weeks, or causing significant psychological distress. Some supplements like biotin and B12 can worsen acne. A dermatologist can identify triggers, prescribe effective treatments, and advise on safe supplement use.

痤疮
Acne

患病率: Affects approximately 85% of people aged 12-24; 12-22% of adult women experience acne

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Evidence-Ranked Ingredients

成分	等级	研究数量	研究方向
Niacinamide	A	15	Positive	查看 →
Zinc	A	12	Positive	查看 →
Vitamin A (Retinol)	C	6	Positive	查看 →
Omega-3 Fatty Acids	C	5	Positive	查看 →
Turmeric (Curcumin)	C	4	Positive	查看 →
Pantothenic Acid	C	3	Positive	查看 →
Green Tea Extract	D	3	Positive	查看 →
Lactobacillus rhamnosus	D	3	Positive	查看 →
Saw Palmetto	D	2	Positive	查看 →

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一种累及毛皮脂腺单位的慢性炎症性皮肤病，特征为粉刺、丘疹、脓疱，可能伴结节或囊肿。发病机制涉及皮脂分泌过多、毛囊角化过度、痤疮丙酸杆菌定植和炎症。