Vitamin A (Retinol)Vitamin A (Retinol)
vitamin
别名: Retinol, Retinyl Palmitate, Retinyl Acetate, Beta-Carotene (provitamin A), Preformed Vitamin A
About
Vitamin A binds retinoic acid receptors (RARs) in skin cells to regulate keratinocyte differentiation, stimulate epidermal turnover, upregulate collagen gene expression, and inhibit matrix metalloproteinases (MMPs) that degrade collagen and elastin. While topical retinoids are the gold standard for photoaging and acne, oral vitamin A at RDA levels supports these processes from within.
How It Works
Binds retinoic acid receptors (RARs) in skin cells to regulate keratinocyte differentiation, stimulate epidermal turnover, upregulate collagen gene expression, and inhibit matrix metalloproteinases (MMPs) that degrade collagen and elastin.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| Acne | C | 6 | 400 | 查看 → |
| Aging Skin & Wrinkles | C | 5 | 300 | 查看 → |
| Keratosis Pilaris | D | 2 | 100 | 查看 → |
Side Effects
- Headache and nausea at high doses
- Skin dryness and peeling (hypervitaminosis A)
- Liver toxicity with chronic excess
- Birth defects (teratogenic — pregnancy contraindication)
Drug & Supplement Interactions
- Retinoid medications (additive toxicity risk — do not combine)
- Tetracycline antibiotics (increased intracranial pressure risk)
- Anticoagulants (high-dose vitamin A may increase bleeding risk)
- Hepatotoxic drugs (additive liver stress)
请务必告知您的医疗保健提供者您正在服用的所有补充剂。
Related Ingredients
FDA 免责声明: 这些声明未经美国食品药品监督管理局(FDA)评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析,不构成医疗建议。在开始任何补充剂方案之前,请务必咨询您的医疗保健提供者。