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Lactobacillus rhamnosus 用于 痤疮

D 研究 目前仅存在初步研究（实验室研究、病例报告）。

Emerging research links gut dysbiosis to acne via the gut-skin axis. Some early studies suggest L. rhamnosus supplementation may help support clear skin.

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            D

        

        

            
结论

            
            
Emerging research links gut dysbiosis to acne via the gut-skin axis. Some early studies suggest L. rhamnosus supplementation may help support clear skin.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Other
                
                
                
                
            

            
                Milk Fat Globules: 2024 Updates.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Inflammatory markers
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: None

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Approach to probiotics in pediatrics: the role of Lactobacillus rhamnosus GG.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Diarrhea, colic, allergy, atopic dermatitis
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: Pediatric patients

            
        

        
        

            

                
                    Randomized Controlled Trial
                
                
                n=90
                
                
                
                Open-label
                
            

            
                Frequency of Antibiotic-Associated Diarrhea and Related Complications in Pediatric Patients Who Underwent Hypospadias Repair: a …
            
            

                
                Dose: 2016. G
                
                
                vs: Antibiotics only or antibiotics + placebo
                
                
                Outcome: AAD incidence post-surgery
                
                
                效果: None
                
                
                pp0.002
                
            

            
            
研究人群: Boys undergoing hypospadias repair

            
        

        
        

            

                
                    Randomized Controlled Trial
                
                
                
                
            

            
                [Effectiveness and safety of probiotics in children on the basis of clinical trials].
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: diarrhea
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: None

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
3

        
研究数量

    

    

        
200

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        D

        
等级

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Milk Fat Globules: 2024 Updates.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Newborn (Clarksville, Md.)
                        2024
                        
                        9 次引用
                        
                    

                

                
                

                    

                        
                            Approach to probiotics in pediatrics: the role of Lactobacillus rhamnosus GG.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Archivos argentinos de …
                        2022
                        
                        23 次引用
                        
                    

                

                
                

                    

                        
                            Frequency of Antibiotic-Associated Diarrhea and Related Complications in Pediatric Patients Who Underwent Hypospadias Repair: a Comparative Study Using Probiotics vs …
                        
                        
                            
                                RCT
                            
                            
                            
                        
                    

                    

                        Probiotics and antimicrobial …
                        2018
                        
                        26 次引用
                        
                    

                

                
                

                    

                        
                            [Effectiveness and safety of probiotics in children on the basis of clinical trials].
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Medycyna wieku rozwojowego
                        2012
                        
                        1 次引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
1-10 billion CFU/day

                    

                    
                    

                        
atopicdermatitis:

                        
10 billion CFU/day L. rhamnosus GG

                    

                    
                

                
                

                    上限： Not established; generally well-tolerated at doses up to 100 billion CFU/day
                

                
            

            

            
            

                
研究中使用的剂量

                

                    

                        
                            

                                剂量
                                持续时间
                                效果
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                2016. G
                                --
                                
                                    
                                    Positive
                                    
                                
                                90
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                最佳服用时间： Before or with meals; some studies suggest empty stomach
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Mild gas or bloating (temporary, during initial use)
                        
    • 
                        
                        
  • 
                            ⚠
                            Rare infections in severely immunocompromised individuals
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Immunosuppressants (theoretical concern — live bacteria)
                        
    • 
                        
                        
  • 
                            ●
                            Antibiotics (may reduce probiotic viability — separate by 2+ hours)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： Not established; generally well-tolerated at doses up to 100 billion CFU/day
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Lactobacillus rhamnosus help with 痤疮?
            
        
        

            Based on 3 studies with 200 participants, there is preliminary evidence that needs more research that Lactobacillus rhamnosus may support 痤疮 management. Our evidence grade is D (Very Early Research).
        

    

    
    

        
            How much Lactobacillus rhamnosus should I take for 痤疮?
            
        
        

            Studies have used various dosages. A commonly studied range is 1-10 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Lactobacillus rhamnosus?
            
        
        

            Reported side effects may include Mild gas or bloating (temporary, during initial use), Rare infections in severely immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Lactobacillus rhamnosus and 痤疮?
            
        
        

            We rate the evidence as Grade D (Very Early Research). This rating is based on 3 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Lactobacillus rhamnosus 用于其他健康状况

                    

                        
                        
                            湿疹（特应性皮炎）
                            B

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Akhil Maheshwari et al..
      Newborn (Clarksville).
      2024.
      Milk Fat Globules: 2024 Updates.
      doi:10.5005/jp-journals-11002-0085
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Christian Boggio Marzet et al..
      Arch Argent Pediatr.
      2022.
      Approach to probiotics in pediatrics: the role of Lactobacillus rhamnosus GG.
      doi:10.5546/aap.2022.eng.e1
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Ciro Esposito et al..
      Probiotics Antimicrob Proteins.
      2018.
      Frequency of Antibiotic-Associated Diarrhea and Related Complications in Pediatric Patients Who Underwent Hypospadias Repair: a Comparative Study Using Probiotics vs …
      doi:10.1007/s12602-017-9324-4
      PubMed
    
    4. 
    
    
  4. 
      [4]
      Ewa Kamińska.
      Med Wieku Rozwoj.
      2012.
      [Effectiveness and safety of probiotics in children on the basis of clinical trials].
      
      PubMed
    
    5. 
    
  















    

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