Vitamin D 관련 백반증
D 연구 예비 연구(실험실 연구, 증례 보고)만 존재합니다.Research suggests vitamin D deficiency is common in vitiligo patients. Supplementation may support melanocyte function, but clinical evidence for repigmentation is limited.
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D
결론
Research suggests vitamin D deficiency is common in vitiligo patients. Supplementation may support melanocyte function, but clinical evidence for repigmentation is limited.
Key Study Findings
retrospective observational with Mendelian randomization
Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study.
Dose: None
vs: Placebo
효과: OR 1.86 (95% CI 1.19-2.92)
0.007
Observational Study
n=573
Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients.
Dose: None
vs: None
Outcome: Vitiligo prevalence and clinical characteristics
효과: None
None
대상 집단: Saudi patients with vitiligo (573)
Meta-Analysis
n=680823
Comorbid Conditions Associated with Alopecia Areata: A Systematic Review and Meta-analysis.
Dose: None
vs: Placebo
효과: Vitamin D deficiency OR 10.13 (95% CI 4.24-24.20)
None
Case-control
n=90
Serum brain-derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata …
Dose: None
vs: Placebo
효과: None
p=0.001 (BDNF and vitamin D vs
Observational Study
Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study.
Dose: 36%
vs: None
Outcome: hair regrowth
효과: None
p < 0.05
대상 집단: Aa referred to our hospitals between 2018 and 2021
Other
n=38
36 weeks
Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients.
Dose: 92.1%
vs: None
Outcome: None
효과: None
None
대상 집단: lsa by a paediatric dermatologist
Key Statistics
4
연구
300
참여자
↑
Positive
D
등급
Referenced Papers
Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study.
Other
Skin research and …
2024
Clinical, cosmetic and …
2024
Comorbid Conditions Associated with Alopecia Areata: A Systematic Review and Meta-analysis.
Meta-Analysis
American journal of …
2023
41 인용
Health science reports
2023
3 인용
Journal of cosmetic …
2023
3 인용
Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients.
Other
International journal of …
2021
14 인용
Journal of the …
2020
57 인용
American journal of …
2018
138 인용
Postepy dermatologii i …
2016
59 인용
The British journal …
2014
74 인용
Off-label uses of topical vitamin D in dermatology: a systematic review.
Systematic Review
Journal of cutaneous …
2014
35 인용
Pediatric vitiligo.
Review
Pediatric clinics of …
2014
25 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 600-800 IU/day (RDA)
- skinhealth:
- 1,000-4,000 IU/day (targeting 30-50 ng/mL serum 25(OH)D)
상한량: 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Neutral | 573 |
| None | -- | Positive | 680823 |
| None | -- | Negative | 90 |
| 36% | -- | Mixed | -- |
| 92.1% | 36 weeks | Positive | 38 |
| None | -- | Positive | 8314220 |
| None | -- | Negative | -- |
권장 복용 시간: With meals containing fat for better absorption
Safety & Side Effects
보고된 부작용
- ⚠ Generally well-tolerated at recommended doses
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness)
- ⚠ Kidney stones (rare, at excessive doses)
알려진 상호작용
- ● Thiazide diuretics (may increase calcium levels)
- ● Corticosteroids (may reduce vitamin D absorption)
- ● Orlistat and cholestyramine (reduce absorption of fat-soluble vitamins)
- ● Calcipotriene (additive vitamin D effect)
일일 최대 섭취 허용량: 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Vitamin D help with 백반증?
Based on 4 studies with 300 participants, there is preliminary evidence that needs more research that Vitamin D may support 백반증 management. Our evidence grade is D (Very Early Research).
How much Vitamin D should I take for 백반증?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Generally well-tolerated at recommended doses, Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones (rare, at excessive doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and 백반증?
We rate the evidence as Grade D (Very Early Research). This rating is based on 4 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.
Related Evidence
Vitamin D 다른 건강 상태에 대한 근거
References
- [1] Yuting Cao et al.. Skin Res Technol. 2024. Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study. doi:10.1111/srt.13911 PubMed
- [2] Mohammed Ibrahim AlJasser. Clin Cosmet Investig Dermatol. 2024. Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients. doi:10.2147/CCID.S499794 PubMed
- [3] Sophia Ly et al.. Am J Clin Dermatol. 2023. Comorbid Conditions Associated with Alopecia Areata: A Systematic Review and Meta-analysis. doi:10.1007/s40257-023-00805-4 PubMed
- [4] Elham Hamidpour et al.. Health Sci Rep. 2023. Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study. doi:10.1002/hsr2.1444 PubMed
- [5] N M Dawoud et al.. J Cosmet Dermatol. 2023. Serum brain-derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata and vitiligo patients: A case-control … doi:10.1111/jocd.15725 PubMed
- [6] Basak Yalici-Armagan et al.. Int J Clin Pract. 2021. Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients. doi:10.1111/ijcp.14661 PubMed
- [7] R Z Conic et al.. J Eur Acad Dermatol Venereol. 2020. Comorbidities in pediatric alopecia areata. doi:10.1111/jdv.16727 PubMed
- [8] Elio Kechichian et al.. Am J Clin Dermatol. 2018. Vitamin D and the Skin: An Update for Dermatologists. doi:10.1007/s40257-017-0323-8 PubMed
- [9] Ebru Karagün et al.. Postepy Dermatol Alergol. 2016. The role of serum vitamin D levels in vitiligo. doi:10.5114/pdia.2016.59507 PubMed
- [10] A Aksu Cerman et al.. Br J Dermatol. 2014. Vitamin D deficiency in alopecia areata. doi:10.1111/bjd.12980 PubMed
- [11] Heidi Wat et al.. J Cutan Med Surg. 2014. Off-label uses of topical vitamin D in dermatology: a systematic review. doi:10.2310/7750.2013.13109 PubMed
- [12] Nanette B Silverberg. Pediatr Clin North Am. 2014. Pediatric vitiligo. doi:10.1016/j.pcl.2013.11.008 PubMed
- [13] Michael P Pender. Autoimmune Dis. 2012. CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis. doi:10.1155/2012/189096 PubMed
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.