Vitamin D cho Vitiligo

Q: Does Vitamin D help with Vitiligo?

Based on 4 studies with 300 participants, there is preliminary evidence that needs more research that Vitamin D may support Vitiligo management. Our evidence grade is D (Very Early Research).

Q: How much Vitamin D should I take for Vitiligo?

Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Vitamin D?

Reported side effects may include Generally well-tolerated at recommended doses, Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones (rare, at excessive doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Vitamin D and Vitiligo?

We rate the evidence as Grade D (Very Early Research). This rating is based on 4 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.

D Nghiên cứu Chỉ tồn tại các nghiên cứu sơ bộ (nghiên cứu phòng thí nghiệm, báo cáo ca bệnh).

Research suggests vitamin D deficiency is common in vitiligo patients. Supplementation may support melanocyte function, but clinical evidence for repigmentation is limited.

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Kết luận

Research suggests vitamin D deficiency is common in vitiligo patients. Supplementation may support melanocyte function, but clinical evidence for repigmentation is limited.

Key Study Findings

retrospective observational with Mendelian randomization

Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study.

Dose: None so với: Placebo Hiệu quả: OR 1.86 (95% CI 1.19-2.92) 0.007

Observational Study n=573

Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients.

Dose: None so với: None Outcome: Vitiligo prevalence and clinical characteristics Hiệu quả: None None

Đối tượng nghiên cứu: Saudi patients with vitiligo (573)

Meta-Analysis n=680823

Comorbid Conditions Associated with Alopecia Areata: A Systematic Review and Meta-analysis.

Dose: None so với: Placebo Hiệu quả: Vitamin D deficiency OR 10.13 (95% CI 4.24-24.20) None

Case-control n=90

Serum brain-derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata …

Dose: None so với: Placebo Hiệu quả: None p=0.001 (BDNF and vitamin D vs

Observational Study

Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study.

Dose: 36% so với: None Outcome: hair regrowth Hiệu quả: None p < 0.05

Đối tượng nghiên cứu: Aa referred to our hospitals between 2018 and 2021

Other n=38 36 weeks

Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients.

Dose: 92.1% so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: lsa by a paediatric dermatologist

Key Statistics

Nghiên cứu

300

Người tham gia

↑

Positive

Xếp hạng

Referenced Papers

Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study. Other

Skin research and … 2024

Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients. Other

Clinical, cosmetic and … 2024

Comorbid Conditions Associated with Alopecia Areata: A Systematic Review and Meta-analysis. Meta-Analysis

American journal of … 2023 41 trích dẫn

Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study. Other

Health science reports 2023 3 trích dẫn

Serum brain-derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata and vitiligo patients: A case-control … Other

Journal of cosmetic … 2023 3 trích dẫn

Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients. Other

International journal of … 2021 14 trích dẫn

Comorbidities in pediatric alopecia areata. Other

Journal of the … 2020 57 trích dẫn

Vitamin D and the Skin: An Update for Dermatologists. Review

American journal of … 2018 138 trích dẫn

The role of serum vitamin D levels in vitiligo. Other

Postepy dermatologii i … 2016 59 trích dẫn

Vitamin D deficiency in alopecia areata. Other

The British journal … 2014 74 trích dẫn

Off-label uses of topical vitamin D in dermatology: a systematic review. Systematic Review

Journal of cutaneous … 2014 35 trích dẫn

Pediatric vitiligo. Review

Pediatric clinics of … 2014 25 trích dẫn

CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis. Other

Autoimmune diseases 2012

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:: 600-800 IU/day (RDA)
skinhealth:: 1,000-4,000 IU/day (targeting 30-50 ng/mL serum 25(OH)D)

Giới hạn trên: 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe

Liều lượng đã nghiên cứu

Liều lượng	Thời gian	Hiệu quả	N
None	--	Mixed	--
None	--	Neutral	573
None	--	Positive	680823
None	--	Negative	90
36%	--	Mixed	--
92.1%	36 weeks	Positive	38
None	--	Positive	8314220
None	--	Negative	--

Thời điểm dùng tốt nhất: With meals containing fat for better absorption

Safety & Side Effects

Tác dụng phụ đã được báo cáo

⚠ Generally well-tolerated at recommended doses
⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness)
⚠ Kidney stones (rare, at excessive doses)

Tương tác đã biết

● Thiazide diuretics (may increase calcium levels)
● Corticosteroids (may reduce vitamin D absorption)
● Orlistat and cholestyramine (reduce absorption of fat-soluble vitamins)
● Calcipotriene (additive vitamin D effect)

Mức hấp thụ tối đa cho phép: 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Vitamin D help with Vitiligo?

Based on 4 studies with 300 participants, there is preliminary evidence that needs more research that Vitamin D may support Vitiligo management. Our evidence grade is D (Very Early Research).

How much Vitamin D should I take for Vitiligo?

Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Vitamin D?

Reported side effects may include Generally well-tolerated at recommended doses, Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones (rare, at excessive doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Vitamin D and Vitiligo?

We rate the evidence as Grade D (Very Early Research). This rating is based on 4 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.

Vitamin D cho các tình trạng khác

Psoriasis B Eczema (Atopic Dermatitis) B

Đánh giá nhanh

Research suggests vitamin D deficiency is common in vitiligo patients. Supplementation may support melanocyte function, but clinical evidence for repigmentation is limited.

Evidence Strength30%

Low confidence

Phân tích nghiên cứu

RCT (0)Meta (1)Other (3)

So sánh lựa chọn thay thế

Xem các thành phần khác so sánh như thế nào cho tình trạng này.

Xem tất cả thành phần cho Vitiligo

Tìm hiểu thêm

References

[1] Yuting Cao et al.. Skin Res Technol. 2024. Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study. doi:10.1111/srt.13911 PubMed
[2] Mohammed Ibrahim AlJasser. Clin Cosmet Investig Dermatol. 2024. Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients. doi:10.2147/CCID.S499794 PubMed
[3] Sophia Ly et al.. Am J Clin Dermatol. 2023. Comorbid Conditions Associated with Alopecia Areata: A Systematic Review and Meta-analysis. doi:10.1007/s40257-023-00805-4 PubMed
[4] Elham Hamidpour et al.. Health Sci Rep. 2023. Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study. doi:10.1002/hsr2.1444 PubMed
[5] N M Dawoud et al.. J Cosmet Dermatol. 2023. Serum brain-derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata and vitiligo patients: A case-control … doi:10.1111/jocd.15725 PubMed
[6] Basak Yalici-Armagan et al.. Int J Clin Pract. 2021. Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients. doi:10.1111/ijcp.14661 PubMed
[7] R Z Conic et al.. J Eur Acad Dermatol Venereol. 2020. Comorbidities in pediatric alopecia areata. doi:10.1111/jdv.16727 PubMed
[8] Elio Kechichian et al.. Am J Clin Dermatol. 2018. Vitamin D and the Skin: An Update for Dermatologists. doi:10.1007/s40257-017-0323-8 PubMed
[9] Ebru Karagün et al.. Postepy Dermatol Alergol. 2016. The role of serum vitamin D levels in vitiligo. doi:10.5114/pdia.2016.59507 PubMed
[10] A Aksu Cerman et al.. Br J Dermatol. 2014. Vitamin D deficiency in alopecia areata. doi:10.1111/bjd.12980 PubMed
[11] Heidi Wat et al.. J Cutan Med Surg. 2014. Off-label uses of topical vitamin D in dermatology: a systematic review. doi:10.2310/7750.2013.13109 PubMed
[12] Nanette B Silverberg. Pediatr Clin North Am. 2014. Pediatric vitiligo. doi:10.1016/j.pcl.2013.11.008 PubMed
[13] Michael P Pender. Autoimmune Dis. 2012. CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis. doi:10.1155/2012/189096 PubMed

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Vitamin D cho Vitiligo

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Kết luận

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Liều lượng thường dùng

Liều lượng đã nghiên cứu

Safety & Side Effects

Tác dụng phụ đã được báo cáo

Tương tác đã biết

Frequently Asked Questions

Related Evidence

Vitamin D cho các tình trạng khác

References