Skip to main content
SkinCited

Biotin ： Hair, Skin & Nails Health

C エビデンス 小規模研究からのエビデンスは限られていますが、いくつかの肯定的なシグナルがあります。

Biotin deficiency clearly causes skin and nail problems. However, systematic reviews have found limited evidence that supplementation above adequate intake levels improves outcomes in non-deficient individuals.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'skincited.com'; const params = 'ingredient\u003Dbiotin\u0026condition\u003Dhair\u002Dskin\u002Dnails'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    


    
    

      Widget powered by
      .
      Free, no account required.
    

  




    








    

        

            C

        

        

            
結論

            
            
Biotin deficiency clearly causes skin and nail problems. However, systematic reviews have found limited evidence that supplementation above adequate intake levels improves outcomes in non-deficient individuals.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    review
                
                
                
                
            

            
                Nail Supplements: When, How, and Why?
            
            

                
                Dose: biotin, collagen peptides, solubilized keratin MSM, choline-stabilized orthosilicic acid
                
                
                vs: Placebo
                
                
                
                効果: None
                
                
                None
                
            

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
8

        
研究数

    

    

        
540

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
グレード

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Nail Supplements: When, How, and Why?
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Skin appendage disorders
                        2025
                        
                    

                

                
                

                    

                        
                            Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Journal of photochemistry …
                        2018
                        
                        16 件の引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
30 mcg/day (AI)

                    

                    
                    

                        
skinhairnails:

                        
2,500-5,000 mcg/day

                    

                    
                

                
                

                    上限量： No established UL (water-soluble); may interfere with lab tests at high doses
                

                
            

            

            
            

                
研究で検討された用量

                

                    

                        
                            

                                用量
                                期間
                                効果
                                N
                            

                        
                        
                            
                            

                                biotin, collagen peptides, solubilized keratin MSM, choline-stabilized orthosilicic acid
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                推奨摂取タイミング： With meals for better absorption
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            May cause acne breakouts at high doses (> 5,000 mcg)
                        
    • 
                        
                        
  • 
                            ⚠
                            Interferes with troponin and thyroid laboratory tests
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Laboratory test interference (troponin, thyroid panels, vitamin D assays)
                        
    • 
                        
                        
  • 
                            ●
                            Anticonvulsants (carbamazepine, phenytoin may reduce biotin levels)
                        
    • 
                        
                        
  • 
                            ●
                            Prolonged antibiotic use (may reduce gut biotin synthesis)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： No established UL (water-soluble); may interfere with lab tests at high doses
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Biotin help with Hair, Skin & Nails Health?
            
        
        

            Based on 8 studies with 540 participants, there is limited but promising evidence that Biotin may support Hair, Skin & Nails Health management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Biotin should I take for Hair, Skin & Nails Health?
            
        
        

            Studies have used various dosages. A commonly studied range is 30 mcg/day (AI). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Biotin?
            
        
        

            Reported side effects may include Generally well-tolerated, May cause acne breakouts at high doses (> 5,000 mcg), Interferes with troponin and thyroid laboratory tests. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Biotin and Hair, Skin & Nails Health?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 8 peer-reviewed studies with 540 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                

                    
に関する他の成分： Hair, Skin & Nails Health

                    

                        
                        
                            Silicon (Silica)
                            C

                        
                        
                        
                            Keratin
                            D

                        
                        
                    

                

                

                
                

                    
Biotin 他の症状・状態について

                    

                        
                        
                            Dry Skin
                            D

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Ines Zaraa et al..
      Skin Appendage Disord.
      2025.
      Nail Supplements: When, How, and Why?
      doi:10.1159/000541048
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Thomas Hengl et al..
      J Photochem Photobiol B.
      2018.
      Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes.
      doi:10.1016/j.jphotobiol.2018.09.005
      PubMed
    
    3. 
    
  















    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。