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Biotin para Hair, Skin & Nails Health

C Evidências Evidência limitada de estudos de pequena dimensão, mas existem alguns sinais positivos.

Biotin deficiency clearly causes skin and nail problems. However, systematic reviews have found limited evidence that supplementation above adequate intake levels improves outcomes in non-deficient individuals.

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            C

        

        

            
Conclusão

            
            
Biotin deficiency clearly causes skin and nail problems. However, systematic reviews have found limited evidence that supplementation above adequate intake levels improves outcomes in non-deficient individuals.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    review
                
                
                
                
            

            
                Nail Supplements: When, How, and Why?
            
            

                
                Dose: biotin, collagen peptides, solubilized keratin MSM, choline-stabilized orthosilicic acid
                
                
                vs: Placebo
                
                
                
                Efeito: None
                
                
                None
                
            

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
8

        
Estudos

    

    

        
540

        
Participantes

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Nota

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Nail Supplements: When, How, and Why?
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Skin appendage disorders
                        2025
                        
                    

                

                
                

                    

                        
                            Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Journal of photochemistry …
                        2018
                        
                        16 citações
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosagens Comumente Utilizadas

                

                    
                    

                        
general:

                        
30 mcg/day (AI)

                    

                    
                    

                        
skinhairnails:

                        
2,500-5,000 mcg/day

                    

                    
                

                
                

                    Limite superior: No established UL (water-soluble); may interfere with lab tests at high doses
                

                
            

            

            
            

                
Dosagens Estudadas em Pesquisas

                

                    

                        
                            

                                Dosagem
                                Duração
                                Efeito
                                N
                            

                        
                        
                            
                            

                                biotin, collagen peptides, solubilized keratin MSM, choline-stabilized orthosilicic acid
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Melhor horário: With meals for better absorption
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Efeitos Colaterais Relatados

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            May cause acne breakouts at high doses (> 5,000 mcg)
                        
    • 
                        
                        
  • 
                            ⚠
                            Interferes with troponin and thyroid laboratory tests
                        
    • 
                        
                    

                

                

                
                

                    
Interações Conhecidas

                    
    
                        
                        
  • 
                            ●
                            Laboratory test interference (troponin, thyroid panels, vitamin D assays)
                        
    • 
                        
                        
  • 
                            ●
                            Anticonvulsants (carbamazepine, phenytoin may reduce biotin levels)
                        
    • 
                        
                        
  • 
                            ●
                            Prolonged antibiotic use (may reduce gut biotin synthesis)
                        
    • 
                        
                    

                

                

                
                

                    

                        Ingestão máxima tolerável: No established UL (water-soluble); may interfere with lab tests at high doses
                    

                

                
            

            

                Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Biotin help with Hair, Skin & Nails Health?
            
        
        

            Based on 8 studies with 540 participants, there is limited but promising evidence that Biotin may support Hair, Skin & Nails Health management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Biotin should I take for Hair, Skin & Nails Health?
            
        
        

            Studies have used various dosages. A commonly studied range is 30 mcg/day (AI). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Biotin?
            
        
        

            Reported side effects may include Generally well-tolerated, May cause acne breakouts at high doses (> 5,000 mcg), Interferes with troponin and thyroid laboratory tests. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Biotin and Hair, Skin & Nails Health?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 8 peer-reviewed studies with 540 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                

                    
Outros ingredientes para Hair, Skin & Nails Health

                    

                        
                        
                            Silicon (Silica)
                            C

                        
                        
                        
                            Keratin
                            D

                        
                        
                    

                

                

                
                

                    
Biotin para outras condições

                    

                        
                        
                            Dry Skin
                            D

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Ines Zaraa et al..
      Skin Appendage Disord.
      2025.
      Nail Supplements: When, How, and Why?
      doi:10.1159/000541048
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Thomas Hengl et al..
      J Photochem Photobiol B.
      2018.
      Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes.
      doi:10.1016/j.jphotobiol.2018.09.005
      PubMed
    
    3. 
    
  















    

        Aviso Legal da FDA:
        Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.