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Zinc per Acne

A

A meta-analysis found zinc supplementation (30-45 mg/day for 8-12 weeks) significantly reduced inflammatory acne lesions. Zinc inhibits 5-alpha-reductase, C. acnes growth, and inflammatory cytokines.

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            A

        

        

            
In sintesi

            
            
A meta-analysis found zinc supplementation (30-45 mg/day for 8-12 weeks) significantly reduced inflammatory acne lesions. Zinc inhibits 5-alpha-reductase, C. acnes growth, and inflammatory cytokines.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
12

        
Studi

    

    

        
900

        
Partecipanti

    

    

        
            
            ↑
            
        
        
Positive

    

    

        A

        
Grado

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosaggi di uso comune

                

                    
                    

                        
general:

                        
8-11 mg/day (RDA)

                    

                    
                    

                        
acneskinhealth:

                        
15-30 mg/day

                    

                    
                

                
                

                    Limite massimo: 40 mg/day (elemental zinc — higher doses may cause copper depletion)
                

                
            

            

            

            
            

                Momento migliore per l'assunzione: With meals to reduce nausea; avoid taking with iron or calcium
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Effetti collaterali segnalati

                    
    
                        
                        
  • 
                            ⚠
                            Nausea (especially on empty stomach)
                        
    • 
                        
                        
  • 
                            ⚠
                            Copper depletion with long-term high-dose use
                        
    • 
                        
                        
  • 
                            ⚠
                            Metallic taste
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                    

                

                

                
                

                    
Interazioni note

                    
    
                        
                        
  • 
                            ●
                            Copper supplements (mutual absorption competition — separate by 2+ hours)
                        
    • 
                        
                        
  • 
                            ●
                            Tetracycline and quinolone antibiotics (reduced antibiotic absorption)
                        
    • 
                        
                        
  • 
                            ●
                            Penicillamine (reduced absorption of both)
                        
    • 
                        
                        
  • 
                            ●
                            Iron supplements (competitive absorption)
                        
    • 
                        
                    

                

                

                
                

                    

                        Livello di assunzione massimo tollerabile: 40 mg/day (elemental zinc — higher doses may cause copper depletion)
                    

                

                
            

            

                Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Zinc help with Acne?
            
        
        

            Based on 12 studies with 900 participants, there is strong evidence from multiple clinical trials that Zinc may support Acne management. Our evidence grade is A (Strong Evidence).
        

    

    
    

        
            How much Zinc should I take for Acne?
            
        
        

            Studies have used various dosages. A commonly studied range is 8-11 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Zinc?
            
        
        

            Reported side effects may include Nausea (especially on empty stomach), Copper depletion with long-term high-dose use, Metallic taste, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Zinc and Acne?
            
        
        

            We rate the evidence as Grade A (Strong Evidence). This rating is based on 12 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Zinc per altre condizioni

                    

                        
                        
                            Wound Healing
                            A

                        
                        
                    

                

                
            

        

        

    


    
    












    

        Avvertenza FDA:
        Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.