Elastin 用于 皮肤老化与皱纹
D 研究 目前仅存在初步研究（实验室研究、病例报告）。Preliminary evidence from small studies suggests oral elastin peptides may improve skin elasticity. Very early research — topical applications have more data.
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D
结论
Preliminary evidence from small studies suggests oral elastin peptides may improve skin elasticity. Very early research — topical applications have more data.
Key Study Findings
animal study
A bioactive three-layered skin substitute based on ECM components effectively promotes skin wound healing and …
Dose: three-layered bioactive skin substitute (BT Skin) containing collagen type I, agarose, dermatan sulf
vs: Placebo
效果: None
None
In Vitro
5 weeks
Use of versican variant V3 and versican antisense expression to engineer cultured human skin containing …
Dose: versican V3 or antisense expression
vs: control cultures
Outcome: insoluble elastin deposition in cultured skin
效果: increased elastin aggregates and tissue stiffness
None
研究人群: Cultured human skin (dermal fibroblasts)
In Vitro
3 weeks
A new dermal equivalent: the use of dermal fibroblast culture alone without exogenous materials.
Dose: None
vs: None
Outcome: A new dermal equivalent: the use of dermal …
效果: None
None
研究人群: None
Key Statistics
2
研究数量
100
受试者
↑
Positive
D
等级
Referenced Papers
Materials today. Bio
2025
10 次引用
Journal of tissue …
2017
12 次引用
A new dermal equivalent: the use of dermal fibroblast culture alone without exogenous materials.
Other
Journal of dermatological …
2006
39 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 75-100 mg/day elastin peptides
上限： Not established
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| three-layered bioactive skin substitute (BT Skin) containing collagen type I, agarose, dermatan sulf | -- | Positive | -- |
| versican V3 or antisense expression | 5 weeks | Positive | -- |
| None | 3 weeks | Mixed | -- |
最佳服用时间： With meals
Safety & Side Effects
已报告的副作用
- ⚠ Generally well-tolerated
- ⚠ Rare gastrointestinal discomfort
已知相互作用
- ● No significant drug interactions documented
可耐受最高摄入量： Not established
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Elastin help with 皮肤老化与皱纹?
Based on 2 studies with 100 participants, there is preliminary evidence that needs more research that Elastin may support 皮肤老化与皱纹 management. Our evidence grade is D (Very Early Research).
How much Elastin should I take for 皮肤老化与皱纹?
Studies have used various dosages. A commonly studied range is 75-100 mg/day elastin peptides. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Elastin?
Reported side effects may include Generally well-tolerated, Rare gastrointestinal discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Elastin and 皮肤老化与皱纹?
We rate the evidence as Grade D (Very Early Research). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
Related Evidence
References
- [1] Carlos Chocarro-Wrona et al.. Mater Today Bio. 2025. A bioactive three-layered skin substitute based on ECM components effectively promotes skin wound healing and regeneration. doi:10.1016/j.mtbio.2025.101592 PubMed
- [2] Mervyn J Merrilees et al.. J Tissue Eng Regen Med. 2017. Use of versican variant V3 and versican antisense expression to engineer cultured human skin containing increased content of insoluble elastin. doi:10.1002/term.1913 PubMed
- [3] Dong-Youn Lee et al.. J Dermatol Sci. 2006. A new dermal equivalent: the use of dermal fibroblast culture alone without exogenous materials. doi:10.1016/j.jdermsci.2006.03.007 PubMed
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