Omega-3 Fatty Acids 관련 건선
D 연구 예비 연구(실험실 연구, 증례 보고)만 존재합니다.Some RCTs suggest omega-3 supplementation may modestly improve psoriasis severity through anti-inflammatory effects, but results are inconsistent across trials.
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D
결론
Some RCTs suggest omega-3 supplementation may modestly improve psoriasis severity through anti-inflammatory effects, but results are inconsistent across trials.
Key Study Findings
Review
Naturally derived bioactive compounds as precision modulators of immune and inflammatory mechanisms in psoriatic conditions.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: review of naturally derived bioactive compounds for psoriasis (flavonoids, terpenoids, omega-3, alkaloids)
Review
Medical Nutrition Therapy in Dermatological Diseases: A Joint Consensus Statement of the Italian Association of …
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Patients with acne, HS, or psoriasis
Review
Association between Omega-3 fatty acids and autoimmune disease: Evidence from the umbrella review and Mendelian …
Dose: None
vs: None
Outcome: Colitis severity
효과: None
None
대상 집단: Crohn's disease patients
narrative_review
Nutrition and skin: Kids are not just little people.
Dose: None
vs: Placebo
효과: narrative review; discusses role of nutrition from prenatal period on skin immune responses; highlig
not_applicable
Other
In vivo response of GsdmA3(Dfl)/+ mice to topically applied fish oil - effects on cellular …
Dose: 100 mg
vs: control
Outcome: None
효과: None
None
대상 집단: psoriasis patients
Review
Diet and psoriasis, part III: role of nutritional supplements.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: psoriasis patients
Key Statistics
6
연구
400
참여자
↑
Positive
D
등급
Referenced Papers
Inflammopharmacology
2025
26 인용
Current obesity reports
2025
Autoimmunity reviews
2024
12 인용
Journal of cosmetic …
2022
30 인용
Clinics in dermatology
2016
19 인용
FEBS open bio
2016
1 인용
Journal of the …
2014
93 인용
Current atherosclerosis reports
2004
464 인용
Journal of the …
2002
2016 인용
Drugs
1998
99 인용
Arquivos de gastroenterologia
1996
The American journal …
1991
2278 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 250-500 mg combined EPA/DHA per day
- skinhealth:
- 1,000-2,000 mg/day EPA+DHA
상한량: 3,000 mg/day combined EPA/DHA (FDA GRAS)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| 100 mg | -- | Mixed | -- |
| None | -- | Positive | -- |
| EPA and DHA | -- | Positive | -- |
| Omega-3 fatty acids (EPA, DHA) | -- | Positive | -- |
권장 복용 시간: With meals containing fat for better absorption
Safety & Side Effects
보고된 부작용
- ⚠ Fishy aftertaste or burping
- ⚠ Mild gastrointestinal discomfort
- ⚠ Potential increased bleeding time at very high doses
- ⚠ May lower blood pressure slightly
알려진 상호작용
- ● Anticoagulants and antiplatelet drugs (may increase bleeding risk at high doses)
- ● Blood pressure medications (additive hypotensive effect)
- ● Orlistat (may reduce omega-3 absorption)
일일 최대 섭취 허용량: 3,000 mg/day combined EPA/DHA (FDA GRAS)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Omega-3 Fatty Acids help with 건선?
Based on 6 studies with 400 participants, there is preliminary evidence that needs more research that Omega-3 Fatty Acids may support 건선 management. Our evidence grade is D (Very Early Research).
How much Omega-3 Fatty Acids should I take for 건선?
Studies have used various dosages. A commonly studied range is 250-500 mg combined EPA/DHA per day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Omega-3 Fatty Acids?
Reported side effects may include Fishy aftertaste or burping, Mild gastrointestinal discomfort, Potential increased bleeding time at very high doses, May lower blood pressure slightly. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Omega-3 Fatty Acids and 건선?
We rate the evidence as Grade D (Very Early Research). This rating is based on 6 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: 건선
Omega-3 Fatty Acids 다른 건강 상태에 대한 근거
References
- [1] Ada Radu et al.. Inflammopharmacology. 2025. Naturally derived bioactive compounds as precision modulators of immune and inflammatory mechanisms in psoriatic conditions. doi:10.1007/s10787-024-01602-z PubMed
- [2] Luigi Barrea et al.. Curr Obes Rep. 2025. Medical Nutrition Therapy in Dermatological Diseases: A Joint Consensus Statement of the Italian Association of Dietetics and Clinical Nutrition (ADI), … doi:10.1007/s13679-025-00630-2 PubMed
- [3] Kimsor Hong et al.. Autoimmun Rev. 2024. Association between Omega-3 fatty acids and autoimmune disease: Evidence from the umbrella review and Mendelian randomization analysis. doi:10.1016/j.autrev.2024.103651 PubMed
- [4] Kabir Sardana et al.. J Cosmet Dermatol. 2022. Role of nutritional supplements in selected dermatological disorders: A review. doi:10.1111/jocd.14436 PubMed
- [5] Meagen McCusker et al.. Clin Dermatol. 2016. Nutrition and skin: Kids are not just little people. doi:10.1016/j.clindermatol.2016.07.004 PubMed
- [6] Mohd Hanif Zulfakar et al.. FEBS Open Bio. 2016. In vivo response of GsdmA3(Dfl)/+ mice to topically applied fish oil - effects on cellular markers and macrophages. doi:10.1002/2211-5463.12095 PubMed
- [7] Jillian W Millsop et al.. J Am Acad Dermatol. 2014. Diet and psoriasis, part III: role of nutritional supplements. doi:10.1016/j.jaad.2014.03.016 PubMed
- [8] Trevor A Mori et al.. Curr Atheroscler Rep. 2004. Omega-3 fatty acids and inflammation. doi:10.1007/s11883-004-0087-5 PubMed
- [9] Artemis P Simopoulos. J Am Coll Nutr. 2002. Omega-3 fatty acids in inflammation and autoimmune diseases. doi:10.1080/07315724.2002.10719248 PubMed
- [10] A Heller et al.. Drugs. 1998. Lipid mediators in inflammatory disorders. doi:10.2165/00003495-199855040-00001 PubMed
- [11] C Cukier et al.. Arq Gastroenterol. 1996. [Biological activity of fish oil]. PubMed
- [12] A P Simopoulos. Am J Clin Nutr. 1991. Omega-3 fatty acids in health and disease and in growth and development. doi:10.1093/ajcn/54.3.438 PubMed
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.