N-Acetyl Cysteine 관련 색소침착
C 근거 소규모 연구에서의 근거는 제한적이지만, 일부 긍정적인 신호가 존재합니다.NAC effectively raises intracellular glutathione levels. A controlled trial found NAC (1,200 mg/day) reduced melanin index, potentially through enhanced glutathione-mediated melanin pathway modulation.
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C
결론
NAC effectively raises intracellular glutathione levels. A controlled trial found NAC (1,200 mg/day) reduced melanin index, potentially through enhanced glutathione-mediated melanin pathway modulation.
Key Study Findings
Review
Nanocatalytic Antioxidation: A General Chemical Approach for Alleviating Oxidative Stress in Diseases.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Review of nanocatalytic antioxidation in diseases
Review
Plant-based strategies against aging: Focus on bioactive compounds from medicine-food homology plants.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: None
In Vitro
Improving in vitro induction efficiency of human primordial germ cell-like cells using N2B27 or NAC-based …
Dose: None
vs: GK15 induction without NAC
Outcome: hPGCLC induction efficiency
효과: None
None
대상 집단: Human iPSCs (in vitro)
Other
Milk Fat Globules: 2024 Updates.
Dose: None
vs: None
Outcome: Inflammatory markers
효과: None
None
대상 집단: None
narrative review
New treatment options for the management of restless leg syndrome.
Dose: rotigotine: various doses; gabapentin enacarbil: 600 mg/day (approved dose)
vs: Placebo
효과: None
None
In Vitro
Renoprotection by ACE inhibition or aldosterone blockade is blood pressure-dependent.
Dose: ACE inhibitor or spironolactone + salt diet
vs: Vehicle-treated SHRsp
Outcome: Renal protection and blood pressure
효과: Renal protection was blood-pressure dependent
None
대상 집단: Salt-supplemented stroke-prone SHR rats
Key Statistics
3
연구
150
참여자
↑
Positive
C
등급
Referenced Papers
Phytomedicine : international …
2025
8 인용
Accounts of chemical …
2025
2 인용
Journal of biomedical …
2025
Newborn (Clarksville, Md.)
2024
9 인용
Scientific reports
2022
28 인용
Pharmaceuticals (Basel, Switzerland)
2022
8 인용
The Journal of …
2014
7 인용
Recent patents on …
2012
Hypertension (Dallas, Tex. …
2003
116 인용
Journal of photochemistry …
2003
71 인용
Arzneimittel-Forschung
1985
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 600-1,200 mg/day
- skinhealth:
- 600-1,800 mg/day
상한량: Generally well-tolerated up to 2,400 mg/day
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| rotigotine: various doses; gabapentin enacarbil: 600 mg/day (approved dose) | -- | Positive | -- |
| ACE inhibitor or spironolactone + salt diet | -- | Positive | -- |
| N-acetyl-L-cysteine (NAC) | -- | Positive | -- |
| 3 ml | -- | Neutral | -- |
권장 복용 시간: On an empty stomach for better absorption; or with meals if GI sensitivity
Safety & Side Effects
보고된 부작용
- ⚠ Nausea and vomiting
- ⚠ Diarrhea
- ⚠ Unpleasant sulfur smell
- ⚠ Rare: bronchospasm (in asthmatics)
알려진 상호작용
- ● Nitroglycerin (may enhance vasodilatory effects)
- ● Activated charcoal (reduces NAC absorption)
- ● Anticoagulants (may have mild antiplatelet effects)
일일 최대 섭취 허용량: Generally well-tolerated up to 2,400 mg/day
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does N-Acetyl Cysteine help with 색소침착?
Based on 3 studies with 150 participants, there is limited but promising evidence that N-Acetyl Cysteine may support 색소침착 management. Our evidence grade is C (Some Evidence).
How much N-Acetyl Cysteine should I take for 색소침착?
Studies have used various dosages. A commonly studied range is 600-1,200 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of N-Acetyl Cysteine?
Reported side effects may include Nausea and vomiting, Diarrhea, Unpleasant sulfur smell, Rare: bronchospasm (in asthmatics). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for N-Acetyl Cysteine and 색소침착?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 150 total participants. The overall direction of effect is positive.
Related Evidence
References
- [1] Yun-Fei Zhu et al.. Phytomedicine. 2025. Plant-based strategies against aging: Focus on bioactive compounds from medicine-food homology plants. doi:10.1016/j.phymed.2025.157052 PubMed
- [2] Bowen Yang et al.. Acc Chem Res. 2025. Nanocatalytic Antioxidation: A General Chemical Approach for Alleviating Oxidative Stress in Diseases. doi:10.1021/acs.accounts.5c00408 PubMed
- [3] Gege Yuan et al.. J Biomed Res. 2025. Improving in vitro induction efficiency of human primordial germ cell-like cells using N2B27 or NAC-based medium. doi:10.7555/JBR.38.20240433 PubMed
- [4] Akhil Maheshwari et al.. Newborn (Clarksville). 2024. Milk Fat Globules: 2024 Updates. doi:10.5005/jp-journals-11002-0085 PubMed
- [5] Vanuchawan Wisuitiprot et al.. Sci Rep. 2022. Effects of Acanthus ebracteatus Vahl. extract and verbascoside on human dermal papilla and murine macrophage. doi:10.1038/s41598-022-04966-w PubMed
- [6] Laila Susanti et al.. Pharmaceuticals (Basel). 2022. Anti-Alopecia Activity of Alkaloids Group from Noni Fruit against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In … doi:10.3390/ph15121557 PubMed
- [7] Beatriz Elizabeth Carmona Toro. J Neurosci Nurs. 2014. New treatment options for the management of restless leg syndrome. doi:10.1097/JNN.0000000000000068 PubMed
- [8] Alfredo Rossi et al.. Recent Pat Inflamm Allergy Drug Discov. 2012. Minoxidil use in dermatology, side effects and recent patents. doi:10.2174/187221312800166859 PubMed
- [9] Karen A Griffin et al.. Hypertension. 2003. Renoprotection by ACE inhibition or aldosterone blockade is blood pressure-dependent. doi:10.1161/01.hyp.0000049881.25304.73 PubMed
- [10] N Morley et al.. J Photochem Photobiol B. 2003. N-acetyl-L-cysteine prevents DNA damage induced by UVA, UVB and visible radiation in human fibroblasts. doi:10.1016/j.jphotobiol.2003.06.004 PubMed
- [11] W Losert et al.. Arzneimittelforschung. 1985. Progestogens with antimineralocorticoid activity. PubMed
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.