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Turmeric (Curcumin)
Turmeric (Curcumin)

herb

Noto anche come: Curcumin, Curcuma longa, Turmeric Extract, Curcuminoids

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About





            

                
Curcumin is one of the most studied anti-inflammatory compounds, with demonstrated NF-kB inhibition relevant to psoriasis, acne, and inflammatory skin conditions. The major limitation is oral bioavailability (< 1%); formulations with piperine increase absorption by 2,000%. A pilot study found curcumin may help support skin health in psoriasis.

            

        

        

        
        
        

            

  
How It Works





            

                
Active polyphenol curcumin inhibits NF-kB, AP-1, and STAT3 inflammatory signaling pathways; modulates COX-2 and LOX enzymes; may inhibit tyrosinase for depigmentation effects; antioxidant properties protect against oxidative stress in skin; low oral bioavailability (~1%) improved by piperine or lipid formulations.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                Condizione
                                Grado
                                Studi
                                Partecipanti
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Psoriasis
                                    
                                
                                
                                    C

                                
                                
                                    6
                                
                                
                                    350
                                
                                
                                    
                                        Visualizza →
                                    
                                
                            

                            
                            

                                
                                    
                                        Acne
                                    
                                
                                
                                    C

                                
                                
                                    4
                                
                                
                                    240
                                
                                
                                    
                                        Visualizza →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Gastrointestinal discomfort (nausea, diarrhea)
                
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                    Yellow staining of teeth (powder form)
                
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                    May worsen gallbladder conditions
                
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Drug & Supplement Interactions





            
    
                
                
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                    Anticoagulants (may increase bleeding risk)
                
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                    Antidiabetic medications (may enhance blood sugar lowering)
                
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                    CYP450 substrates (may inhibit drug metabolism)
                
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                    Iron supplements (may reduce absorption)
                
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                Informare sempre il proprio medico di tutti gli integratori che si assumono.Informate sempre il vostro medico di tutti gli integratori che assumete.
            

        

        

        
        
        

            

  




            

                
                
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        Avvertenza FDA:
        Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.