Lactobacillus plantarum
probioticAlso known as: L. plantarum, Lactiplantibacillus plantarum, HY7714
About
Lactobacillus plantarum produces antimicrobial bacteriocins and supports intestinal barrier function. A double-blind RCT found L. plantarum HY7714 (10 billion CFU/day for 12 weeks) significantly improved skin hydration, reduced wrinkle depth, and increased skin elasticity in women aged 41-59.
How It Works
Produces antimicrobial bacteriocins; supports intestinal barrier function by upregulating tight junction proteins (ZO-1, occludin); modulates skin immune responses through gut-skin axis; specific strains (L. plantarum HY7714) shown to improve skin hydration and reduce wrinkle depth.
Evidence For Conditions
| Condition | Grade | Studies | Participants | |
|---|---|---|---|---|
| Aging Skin & Wrinkles | C | 3 | 180 | View → |
| Dry Skin | C | 3 | 180 | View → |
Side Effects
- Mild gas or bloating (temporary)
- Rare infections in severely immunocompromised individuals
Drug & Supplement Interactions
- Immunosuppressants (theoretical concern — live bacteria)
- Antibiotics (may reduce probiotic viability — separate by 2+ hours)
Always inform your healthcare provider about all supplements you take.
Related Ingredients
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.