Skip to main content
SkinCited

Lactobacillus plantarum for Aging Skin & Wrinkles

C Some Evidence Limited evidence from small studies, but some positive signals exist.

Research suggests L. plantarum HY7714 (10 billion CFU/day) may improve skin hydration, wrinkle depth, and elasticity through gut-skin axis modulation. Strain-specific evidence.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'skincited.com'; const params = 'ingredient\u003Dlactobacillus\u002Dplantarum\u0026condition\u003Daging\u002Dskin\u002Dwrinkles'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    


    
    

      Widget powered by
      .
      Free, no account required.
    

  




    








    

        

            C

        

        

            
The Bottom Line

            
            
Research suggests L. plantarum HY7714 (10 billion CFU/day) may improve skin hydration, wrinkle depth, and elasticity through gut-skin axis modulation. Strain-specific evidence.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                The Role of Bifidobacteria in Predictive and Preventive Medicine: A Focus on Eczema and Hypercholesterolemia.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: None
                
                
                Effect: None
                
                
                None
                
            

            
            
Population: Infants/children with eczema risk

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
3

        
Studies

    

    

        
180

        
Participants

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Grade

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Lactiplantibacillus plantarum ZJUIDS51 improves androgenic alopecia via gut-skin axis.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Food research international …
                        2026
                        
                    

                

                
                

                    

                        
                            The Role of Bifidobacteria in Predictive and Preventive Medicine: A Focus on Eczema and Hypercholesterolemia.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Microorganisms
                        2021
                        
                        47 citations
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Commonly Used Dosages

                

                    
                    

                        
general:

                        
1-10 billion CFU/day

                    

                    
                    

                        
skinhealth:

                        
10 billion CFU/day

                    

                    
                

                
                

                    Upper limit: Not established
                

                
            

            

            
            

                
Dosages Studied in Research

                

                    

                        
                            

                                Dosage
                                Duration
                                Effect
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Best taken: With or without meals
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Reported Side Effects

                    
    
                        
                        
  • 
                            ⚠
                            Mild gas or bloating (temporary)
                        
    • 
                        
                        
  • 
                            ⚠
                            Rare infections in severely immunocompromised individuals
                        
    • 
                        
                    

                

                

                
                

                    
Known Interactions

                    
    
                        
                        
  • 
                            ●
                            Immunosuppressants (theoretical concern — live bacteria)
                        
    • 
                        
                        
  • 
                            ●
                            Antibiotics (may reduce probiotic viability — separate by 2+ hours)
                        
    • 
                        
                    

                

                

                
                

                    

                        Tolerable upper intake: Not established
                    

                

                
            

            

                Always consult your healthcare provider before starting any supplement.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Lactobacillus plantarum help with Aging Skin & Wrinkles?
            
        
        

            Based on 3 studies with 180 participants, there is limited but promising evidence that Lactobacillus plantarum may support Aging Skin & Wrinkles management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Lactobacillus plantarum should I take for Aging Skin & Wrinkles?
            
        
        

            Studies have used various dosages. A commonly studied range is 1-10 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Lactobacillus plantarum?
            
        
        

            Reported side effects may include Mild gas or bloating (temporary), Rare infections in severely immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Lactobacillus plantarum and Aging Skin & Wrinkles?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 180 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Lactobacillus plantarum for other conditions

                    

                        
                        
                            Dry Skin
                            C

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Jinfeng Fu et al..
      Food Res Int.
      2026.
      Lactiplantibacillus plantarum ZJUIDS51 improves androgenic alopecia via gut-skin axis.
      doi:10.1016/j.foodres.2026.118793
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Luisa Marras et al..
      Microorganisms.
      2021.
      The Role of Bifidobacteria in Predictive and Preventive Medicine: A Focus on Eczema and Hypercholesterolemia.
      doi:10.3390/microorganisms9040836
      PubMed
    
    3. 
    
  















    

        FDA Disclaimer:
        These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.