Vitamin D untuk Eczema (Atopic Dermatitis)
B Bukti Setidaknya satu uji coba acak mendukung hal ini, dengan hasil yang sebagian besar konsisten.A meta-analysis found vitamin D supplementation was associated with significantly improved SCORAD scores in atopic dermatitis patients, particularly those with documented vitamin D deficiency.
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B
Kesimpulan
A meta-analysis found vitamin D supplementation was associated with significantly improved SCORAD scores in atopic dermatitis patients, particularly those with documented vitamin D deficiency.
Key Study Findings
Observational Study
n=573
Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients.
Dose: None
vs: None
Outcome: Vitiligo prevalence and clinical characteristics
Efek: None
None
Populasi: Saudi patients with vitiligo (573)
retrospective observational with Mendelian randomization
Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study.
Dose: None
vs: Placebo
Efek: OR 1.86 (95% CI 1.19-2.92)
0.007
Review
Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why.
Dose: 14 nutritional compounds (vitamins, minerals, etc.)
vs: None
Outcome: Skin health and barrier function
Efek: None
None
Populasi: General population (skin health review)
Review
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases.
Dose: None
vs: None
Outcome: hair regrowth
Efek: None
None
Populasi: None
Case Reports
Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation?
Dose: None
vs: None
Outcome: Atopic dermatitis symptoms
Efek: None
None
Populasi: Patients with atopic dermatitis
Other
Nutrition and Atopic Dermatitis.
Dose: None
vs: None
Outcome: None
Efek: None
None
Populasi: None
Key Statistics
12
Studi
1800
Peserta
↑
Positive
B
Peringkat
Referenced Papers
Clinical, cosmetic and …
2024
Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study.
Other
Skin research and …
2024
Medicina (Kaunas, Lithuania)
2023
41 sitasi
Mini reviews in …
2023
9 sitasi
Journal of dietary …
2022
6 sitasi
Journal of Nippon …
2021
26 sitasi
Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients.
Other
International journal of …
2021
14 sitasi
Alternative therapies in …
2021
10 sitasi
Journal of the …
2020
57 sitasi
The World Allergy …
2020
16 sitasi
Actas dermo-sifiliograficas
2019
43 sitasi
American journal of …
2018
138 sitasi
International journal of …
2016
22 sitasi
Clinics in dermatology
2016
19 sitasi
Dietary supplements for established atopic eczema.
Meta-Analysis
The Cochrane database …
2012
130 sitasi
Acta scientiarum polonorum. …
2012
11 sitasi
[The treatment of alopecia areata and of dyshidrotic eczema with milk protein bound vitamin D 2].
Other
Deutsche medizinische Wochenschrift …
1955
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- general:
- 600-800 IU/day (RDA)
- skinhealth:
- 1,000-4,000 IU/day (targeting 30-50 ng/mL serum 25(OH)D)
Batas atas: 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Neutral | 573 |
| None | -- | Mixed | -- |
| 14 nutritional compounds (vitamins, minerals, etc.) | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 92.1% | 36 weeks | Positive | 38 |
Waktu terbaik diminum: With meals containing fat for better absorption
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Generally well-tolerated at recommended doses
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness)
- ⚠ Kidney stones (rare, at excessive doses)
Interaksi yang Diketahui
- ● Thiazide diuretics (may increase calcium levels)
- ● Corticosteroids (may reduce vitamin D absorption)
- ● Orlistat and cholestyramine (reduce absorption of fat-soluble vitamins)
- ● Calcipotriene (additive vitamin D effect)
Asupan atas yang dapat ditoleransi: 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Vitamin D help with Eczema (Atopic Dermatitis)?
Based on 12 studies with 1,800 participants, there is moderate evidence from clinical studies that Vitamin D may support Eczema (Atopic Dermatitis) management. Our evidence grade is B (Good Evidence).
How much Vitamin D should I take for Eczema (Atopic Dermatitis)?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Generally well-tolerated at recommended doses, Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones (rare, at excessive doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Eczema (Atopic Dermatitis)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 1,800 total participants. The overall direction of effect is positive.
Related Evidence
Bahan lain untuk Eczema (Atopic Dermatitis)
Vitamin D untuk kondisi lain
References
- [1] Mohammed Ibrahim AlJasser. Clin Cosmet Investig Dermatol. 2024. Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients. doi:10.2147/CCID.S499794 PubMed
- [2] Yuting Cao et al.. Skin Res Technol. 2024. Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study. doi:10.1111/srt.13911 PubMed
- [3] Jacek Januszewski et al.. Medicina (Kaunas). 2023. Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why. doi:10.3390/medicina60010068 PubMed
- [4] Yilan Zeng et al.. Mini Rev Med Chem. 2023. The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases. doi:10.2174/1389557523666221124123206 PubMed
- [5] Davide Chesini Ms et al.. J Diet Suppl. 2022. Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation? doi:10.1080/19390211.2020.1860180 PubMed
- [6] Naoko Kanda et al.. J Nippon Med Sch. 2021. Nutrition and Atopic Dermatitis. doi:10.1272/jnms.JNMS.2021_88-317 PubMed
- [7] Basak Yalici-Armagan et al.. Int J Clin Pract. 2021. Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients. doi:10.1111/ijcp.14661 PubMed
- [8] Kathleen M Coerdt et al.. Altern Ther Health Med. 2021. Vitamins A, B, C, and D: A Short Review for the Dermatologist. PubMed
- [9] R Z Conic et al.. J Eur Acad Dermatol Venereol. 2020. Comorbidities in pediatric alopecia areata. doi:10.1111/jdv.16727 PubMed
- [10] Amare Abera Tareke et al.. World Allergy Organ J. 2020. Prenatal vitamin D supplementation and child respiratory health: A systematic review and meta-analysis of randomized controlled trials. doi:10.1016/j.waojou.2020.100486 PubMed
- [11] F J Navarro-Triviño et al.. Actas Dermosifiliogr (Engl Ed). 2019. Vitamin D and the Skin: A Review for Dermatologists. doi:10.1016/j.ad.2018.08.006 PubMed
- [12] Elio Kechichian et al.. Am J Clin Dermatol. 2018. Vitamin D and the Skin: An Update for Dermatologists. doi:10.1007/s40257-017-0323-8 PubMed
- [13] Ozlem Atan Sahin et al.. Int J Pediatr Otorhinolaryngol. 2016. The association of residential mold exposure and adenotonsillar hypertrophy in children living in damp environments. doi:10.1016/j.ijporl.2016.07.018 PubMed
- [14] Meagen McCusker et al.. Clin Dermatol. 2016. Nutrition and skin: Kids are not just little people. doi:10.1016/j.clindermatol.2016.07.004 PubMed
- [15] Fiona J Bath-Hextall et al.. Cochrane Database Syst Rev. 2012. Dietary supplements for established atopic eczema. doi:10.1002/14651858.CD005205.pub3 PubMed
- [16] Carlos Lifschitz. Acta Sci Pol Technol Aliment. 2012. New actions for old nutrients. PubMed
- [17] W SCHUCHARD. Dtsch Med Wochenschr. 1955. [The treatment of alopecia areata and of dyshidrotic eczema with milk protein bound vitamin D 2]. doi:10.1055/s-0028-1116437 PubMed
Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.