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Vitamin D pour Eczema (Atopic Dermatitis)

B Preuves Au moins un essai randomisé le soutient, avec des résultats globalement concordants.

A meta-analysis found vitamin D supplementation was associated with significantly improved SCORAD scores in atopic dermatitis patients, particularly those with documented vitamin D deficiency.

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B

En conclusion

A meta-analysis found vitamin D supplementation was associated with significantly improved SCORAD scores in atopic dermatitis patients, particularly those with documented vitamin D deficiency.

Key Study Findings

Observational Study n=573
Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients.
Dose: None vs: None Outcome: Vitiligo prevalence and clinical characteristics Effet: None None

Population: Saudi patients with vitiligo (573)

retrospective observational with Mendelian randomization
Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study.
Dose: None vs: Placebo Effet: OR 1.86 (95% CI 1.19-2.92) 0.007
Review
Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why.
Dose: 14 nutritional compounds (vitamins, minerals, etc.) vs: None Outcome: Skin health and barrier function Effet: None None

Population: General population (skin health review)

Review
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases.
Dose: None vs: None Outcome: hair regrowth Effet: None None

Population: None

Case Reports
Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation?
Dose: None vs: None Outcome: Atopic dermatitis symptoms Effet: None None

Population: Patients with atopic dermatitis

Other
Nutrition and Atopic Dermatitis.
Dose: None vs: None Outcome: None Effet: None None

Population: None

Key Statistics

12

Études

1800

Participants

Positive

B

Note

Referenced Papers

Journal of Nippon … 2021 26 citations
Alternative therapies in … 2021 10 citations
Journal of the … 2020 57 citations
Actas dermo-sifiliograficas 2019 43 citations
American journal of … 2018 138 citations
Clinics in dermatology 2016 19 citations
The Cochrane database … 2012 130 citations
Acta scientiarum polonorum. … 2012 11 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:
600-800 IU/day (RDA)
skinhealth:
1,000-4,000 IU/day (targeting 30-50 ng/mL serum 25(OH)D)

Limite supérieure : 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe

Posologies étudiées dans la recherche

Posologie Durée Effet N
None -- Neutral 573
None -- Mixed --
14 nutritional compounds (vitamins, minerals, etc.) -- Positive --
None -- Mixed --
None -- Positive --
None -- Positive --
None -- Positive --
92.1% 36 weeks Positive 38

Moment optimal de prise : With meals containing fat for better absorption

Safety & Side Effects

Effets indésirables signalés

  • Generally well-tolerated at recommended doses
  • Hypercalcemia at very high doses (nausea, vomiting, weakness)
  • Kidney stones (rare, at excessive doses)

Interactions connues

  • Thiazide diuretics (may increase calcium levels)
  • Corticosteroids (may reduce vitamin D absorption)
  • Orlistat and cholestyramine (reduce absorption of fat-soluble vitamins)
  • Calcipotriene (additive vitamin D effect)

Apport maximal tolérable : 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Vitamin D help with Eczema (Atopic Dermatitis)?
Based on 12 studies with 1,800 participants, there is moderate evidence from clinical studies that Vitamin D may support Eczema (Atopic Dermatitis) management. Our evidence grade is B (Good Evidence).
How much Vitamin D should I take for Eczema (Atopic Dermatitis)?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Generally well-tolerated at recommended doses, Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones (rare, at excessive doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Eczema (Atopic Dermatitis)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 1,800 total participants. The overall direction of effect is positive.

Vitamin D pour d'autres pathologies

References

  1. [1] Mohammed Ibrahim AlJasser. Clin Cosmet Investig Dermatol. 2024. Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients. doi:10.2147/CCID.S499794 PubMed
  2. [2] Yuting Cao et al.. Skin Res Technol. 2024. Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study. doi:10.1111/srt.13911 PubMed
  3. [3] Jacek Januszewski et al.. Medicina (Kaunas). 2023. Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why. doi:10.3390/medicina60010068 PubMed
  4. [4] Yilan Zeng et al.. Mini Rev Med Chem. 2023. The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases. doi:10.2174/1389557523666221124123206 PubMed
  5. [5] Davide Chesini Ms et al.. J Diet Suppl. 2022. Vitamin B12 and Atopic Dermatitis: Any Therapeutic Relevance For Oral Supplementation? doi:10.1080/19390211.2020.1860180 PubMed
  6. [6] Naoko Kanda et al.. J Nippon Med Sch. 2021. Nutrition and Atopic Dermatitis. doi:10.1272/jnms.JNMS.2021_88-317 PubMed
  7. [7] Basak Yalici-Armagan et al.. Int J Clin Pract. 2021. Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients. doi:10.1111/ijcp.14661 PubMed
  8. [8] Kathleen M Coerdt et al.. Altern Ther Health Med. 2021. Vitamins A, B, C, and D: A Short Review for the Dermatologist. PubMed
  9. [9] R Z Conic et al.. J Eur Acad Dermatol Venereol. 2020. Comorbidities in pediatric alopecia areata. doi:10.1111/jdv.16727 PubMed
  10. [10] Amare Abera Tareke et al.. World Allergy Organ J. 2020. Prenatal vitamin D supplementation and child respiratory health: A systematic review and meta-analysis of randomized controlled trials. doi:10.1016/j.waojou.2020.100486 PubMed
  11. [11] F J Navarro-Triviño et al.. Actas Dermosifiliogr (Engl Ed). 2019. Vitamin D and the Skin: A Review for Dermatologists. doi:10.1016/j.ad.2018.08.006 PubMed
  12. [12] Elio Kechichian et al.. Am J Clin Dermatol. 2018. Vitamin D and the Skin: An Update for Dermatologists. doi:10.1007/s40257-017-0323-8 PubMed
  13. [13] Ozlem Atan Sahin et al.. Int J Pediatr Otorhinolaryngol. 2016. The association of residential mold exposure and adenotonsillar hypertrophy in children living in damp environments. doi:10.1016/j.ijporl.2016.07.018 PubMed
  14. [14] Meagen McCusker et al.. Clin Dermatol. 2016. Nutrition and skin: Kids are not just little people. doi:10.1016/j.clindermatol.2016.07.004 PubMed
  15. [15] Fiona J Bath-Hextall et al.. Cochrane Database Syst Rev. 2012. Dietary supplements for established atopic eczema. doi:10.1002/14651858.CD005205.pub3 PubMed
  16. [16] Carlos Lifschitz. Acta Sci Pol Technol Aliment. 2012. New actions for old nutrients. PubMed
  17. [17] W SCHUCHARD. Dtsch Med Wochenschr. 1955. [The treatment of alopecia areata and of dyshidrotic eczema with milk protein bound vitamin D 2]. doi:10.1055/s-0028-1116437 PubMed

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