Vitamin D pour Vitiligo

Q: Does Vitamin D help with Vitiligo?

Based on 4 studies with 300 participants, there is preliminary evidence that needs more research that Vitamin D may support Vitiligo management. Our evidence grade is D (Very Early Research).

Q: How much Vitamin D should I take for Vitiligo?

Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Vitamin D?

Reported side effects may include Generally well-tolerated at recommended doses, Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones (rare, at excessive doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Vitamin D and Vitiligo?

We rate the evidence as Grade D (Very Early Research). This rating is based on 4 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.

D Recherche Seules des recherches préliminaires existent (études en laboratoire, rapports de cas).

Research suggests vitamin D deficiency is common in vitiligo patients. Supplementation may support melanocyte function, but clinical evidence for repigmentation is limited.

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En conclusion

Research suggests vitamin D deficiency is common in vitiligo patients. Supplementation may support melanocyte function, but clinical evidence for repigmentation is limited.

Key Study Findings

retrospective observational with Mendelian randomization

Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study.

Dose: None vs: Placebo Effet: OR 1.86 (95% CI 1.19-2.92) 0.007

Observational Study n=573

Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients.

Dose: None vs: None Outcome: Vitiligo prevalence and clinical characteristics Effet: None None

Population: Saudi patients with vitiligo (573)

Meta-Analysis n=680823

Comorbid Conditions Associated with Alopecia Areata: A Systematic Review and Meta-analysis.

Dose: None vs: Placebo Effet: Vitamin D deficiency OR 10.13 (95% CI 4.24-24.20) None

Case-control n=90

Serum brain-derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata …

Dose: None vs: Placebo Effet: None p=0.001 (BDNF and vitamin D vs

Observational Study

Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study.

Dose: 36% vs: None Outcome: hair regrowth Effet: None p < 0.05

Population: Aa referred to our hospitals between 2018 and 2021

Other n=38 36 weeks

Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients.

Dose: 92.1% vs: None Outcome: None Effet: None None

Population: lsa by a paediatric dermatologist

Key Statistics

Études

300

Participants

↑

Positive

Note

Referenced Papers

Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study. Other

Skin research and … 2024

Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients. Other

Clinical, cosmetic and … 2024

Comorbid Conditions Associated with Alopecia Areata: A Systematic Review and Meta-analysis. Meta-Analysis

American journal of … 2023 41 citations

Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study. Other

Health science reports 2023 3 citations

Serum brain-derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata and vitiligo patients: A case-control … Other

Journal of cosmetic … 2023 3 citations

Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients. Other

International journal of … 2021 14 citations

Comorbidities in pediatric alopecia areata. Other

Journal of the … 2020 57 citations

Vitamin D and the Skin: An Update for Dermatologists. Review

American journal of … 2018 138 citations

The role of serum vitamin D levels in vitiligo. Other

Postepy dermatologii i … 2016 59 citations

Vitamin D deficiency in alopecia areata. Other

The British journal … 2014 74 citations

Off-label uses of topical vitamin D in dermatology: a systematic review. Systematic Review

Journal of cutaneous … 2014 35 citations

Pediatric vitiligo. Review

Pediatric clinics of … 2014 25 citations

CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis. Other

Autoimmune diseases 2012

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:: 600-800 IU/day (RDA)
skinhealth:: 1,000-4,000 IU/day (targeting 30-50 ng/mL serum 25(OH)D)

Limite supérieure : 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe

Posologies étudiées dans la recherche

Posologie	Durée	Effet	N
None	--	Mixed	--
None	--	Neutral	573
None	--	Positive	680823
None	--	Negative	90
36%	--	Mixed	--
92.1%	36 weeks	Positive	38
None	--	Positive	8314220
None	--	Negative	--

Moment optimal de prise : With meals containing fat for better absorption

Safety & Side Effects

Effets indésirables signalés

⚠ Generally well-tolerated at recommended doses
⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness)
⚠ Kidney stones (rare, at excessive doses)

Interactions connues

● Thiazide diuretics (may increase calcium levels)
● Corticosteroids (may reduce vitamin D absorption)
● Orlistat and cholestyramine (reduce absorption of fat-soluble vitamins)
● Calcipotriene (additive vitamin D effect)

Apport maximal tolérable : 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Vitamin D help with Vitiligo?

Based on 4 studies with 300 participants, there is preliminary evidence that needs more research that Vitamin D may support Vitiligo management. Our evidence grade is D (Very Early Research).

How much Vitamin D should I take for Vitiligo?

Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Vitamin D?

Reported side effects may include Generally well-tolerated at recommended doses, Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones (rare, at excessive doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Vitamin D and Vitiligo?

We rate the evidence as Grade D (Very Early Research). This rating is based on 4 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.

Vitamin D pour d'autres pathologies

Psoriasis B Eczema (Atopic Dermatitis) B

Verdict rapide

Research suggests vitamin D deficiency is common in vitiligo patients. Supplementation may support melanocyte function, but clinical evidence for repigmentation is limited.

Evidence Strength30%

Low confidence

Synthèse des études

RCT (0)Meta (1)Other (3)

Comparer les alternatives

Découvrez comment d'autres ingrédients se comparent pour cette condition.Découvrez comment d'autres ingrédients se comparent pour cette pathologie.

Voir tous les ingrédients pour Vitiligo

En savoir plus

References

[1] Yuting Cao et al.. Skin Res Technol. 2024. Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study. doi:10.1111/srt.13911 PubMed
[2] Mohammed Ibrahim AlJasser. Clin Cosmet Investig Dermatol. 2024. Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients. doi:10.2147/CCID.S499794 PubMed
[3] Sophia Ly et al.. Am J Clin Dermatol. 2023. Comorbid Conditions Associated with Alopecia Areata: A Systematic Review and Meta-analysis. doi:10.1007/s40257-023-00805-4 PubMed
[4] Elham Hamidpour et al.. Health Sci Rep. 2023. Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study. doi:10.1002/hsr2.1444 PubMed
[5] N M Dawoud et al.. J Cosmet Dermatol. 2023. Serum brain-derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata and vitiligo patients: A case-control … doi:10.1111/jocd.15725 PubMed
[6] Basak Yalici-Armagan et al.. Int J Clin Pract. 2021. Paediatric lichen sclerosus et atrophicus: A retrospective analysis of 38 paediatric patients. doi:10.1111/ijcp.14661 PubMed
[7] R Z Conic et al.. J Eur Acad Dermatol Venereol. 2020. Comorbidities in pediatric alopecia areata. doi:10.1111/jdv.16727 PubMed
[8] Elio Kechichian et al.. Am J Clin Dermatol. 2018. Vitamin D and the Skin: An Update for Dermatologists. doi:10.1007/s40257-017-0323-8 PubMed
[9] Ebru Karagün et al.. Postepy Dermatol Alergol. 2016. The role of serum vitamin D levels in vitiligo. doi:10.5114/pdia.2016.59507 PubMed
[10] A Aksu Cerman et al.. Br J Dermatol. 2014. Vitamin D deficiency in alopecia areata. doi:10.1111/bjd.12980 PubMed
[11] Heidi Wat et al.. J Cutan Med Surg. 2014. Off-label uses of topical vitamin D in dermatology: a systematic review. doi:10.2310/7750.2013.13109 PubMed
[12] Nanette B Silverberg. Pediatr Clin North Am. 2014. Pediatric vitiligo. doi:10.1016/j.pcl.2013.11.008 PubMed
[13] Michael P Pender. Autoimmune Dis. 2012. CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis. doi:10.1155/2012/189096 PubMed

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.

Vitamin D pour Vitiligo

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En conclusion

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Posologies couramment utilisées

Posologies étudiées dans la recherche

Safety & Side Effects

Effets indésirables signalés

Interactions connues

Frequently Asked Questions

Related Evidence

Vitamin D pour d'autres pathologies

References