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SkinCited

Selenium 用于 UV Protection (Internal Photoprotection)

C

The SU.VI.MAX trial suggests selenium-containing antioxidant supplements may reduce skin cancer risk in men. Selenium supports glutathione peroxidase-mediated protection against UV-induced oxidative damage.

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结论

            
            
The SU.VI.MAX trial suggests selenium-containing antioxidant supplements may reduce skin cancer risk in men. Selenium supports glutathione peroxidase-mediated protection against UV-induced oxidative damage.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
5

        
研究数量

    

    

        
1800

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
等级

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
55 mcg/day (RDA)

                    

                    
                    

                        
skinhealth:

                        
55-200 mcg/day

                    

                    
                

                
                

                    上限： 400 mcg/day (toxicity: selenosis)
                

                
            

            

            

            
            

                最佳服用时间： With meals
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Garlic breath odor
                        
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                            ⚠
                            Nail brittleness and loss (selenosis)
                        
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                            ⚠
                            Hair loss (at toxic doses)
                        
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  • 
                            ⚠
                            Gastrointestinal disturbances
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Cisplatin and other chemotherapy (may reduce drug efficacy)
                        
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  • 
                            ●
                            Statins (may affect selenium status)
                        
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  • 
                            ●
                            Blood thinners (theoretical interaction)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： 400 mcg/day (toxicity: selenosis)
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Selenium help with UV Protection (Internal Photoprotection)?
            
        
        

            Based on 5 studies with 1,800 participants, there is limited but promising evidence that Selenium may support UV Protection (Internal Photoprotection) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Selenium should I take for UV Protection (Internal Photoprotection)?
            
        
        

            Studies have used various dosages. A commonly studied range is 55 mcg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Selenium?
            
        
        

            Reported side effects may include Garlic breath odor, Nail brittleness and loss (selenosis), Hair loss (at toxic doses), Gastrointestinal disturbances. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Selenium and UV Protection (Internal Photoprotection)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 1,800 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

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