Zinc cho Wound Healing

A Bằng chứng Nhiều thử nghiệm lâm sàng lớn liên tục cho thấy những lợi ích đáng kể.

Well-established evidence that zinc is essential for wound healing. Zinc deficiency impairs all phases of repair. Supplementation in deficient individuals may help accelerate wound closure.

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Kết luận

Well-established evidence that zinc is essential for wound healing. Zinc deficiency impairs all phases of repair. Supplementation in deficient individuals may help accelerate wound closure.

Key Study Findings

Review

UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …

Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: Elite/professional cyclists nutrition review

Observational Study

Combining Metabolomics and Proteomics to Reveal Key Serum Compounds Related to Canine Intervertebral Disc Herniation.

Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: Dogs with intervertebral disc herniation

In Vitro

Glucose-responsive multifunctional hydrogel incorporating GOx@ZIF-8 for NO/Zn2+-mediated antibacterial and pro-angiogenic diabetic wound healing.

Dose: None so với: None Outcome: Diabetic wound healing Hiệu quả: None None

Đối tượng nghiên cứu: Diabetic wound model

Systematic Review

Impact of oral nutritional supplement composition on healing of different chronic wounds: A systematic review.

Dose: None so với: Control Outcome: Wound healing Hiệu quả: None None

Đối tượng nghiên cứu: Diabetic patients

In Vitro

Preparation and evaluation of a novel alginate-arginine-zinc ion hydrogel film for skin wound healing.

Dose: SA-Arg-Zn2+ hydrogel so với: Other dressing materials Outcome: Wound healing, antibacterial, antioxidant Hiệu quả: None None

Đối tượng nghiên cứu: In vitro + animal wound model

Other

[Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot].

Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: chronic wounds and have been linked to delayed wound healing and dehiscence

Key Statistics

Nghiên cứu

1500

Người tham gia

↑

Positive

Xếp hạng

Referenced Papers

Glucose-responsive multifunctional hydrogel incorporating GOx@ZIF-8 for NO/Zn2+-mediated antibacterial and pro-angiogenic diabetic wound healing. Other

Journal of colloid … 2025 8 trích dẫn

UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses and Injuries in Elite Cycling. Other

International journal of … 2025 2 trích dẫn

Combining Metabolomics and Proteomics to Reveal Key Serum Compounds Related to Canine Intervertebral Disc Herniation. Other

Metabolites 2025

Impact of oral nutritional supplement composition on healing of different chronic wounds: A systematic review. Systematic Review

Nutrition (Burbank, Los … 2024 12 trích dẫn

Preparation and evaluation of a novel alginate-arginine-zinc ion hydrogel film for skin wound healing. Other

Carbohydrate polymers 2023 86 trích dẫn

Curcumin-zinc framework encapsulated microneedle patch for promoting hair growth. Other

Theranostics 2023 65 trích dẫn

A review on bioactive phytochemicals and ethnopharmacological potential of purslane (Portulaca oleracea L.). Review

Heliyon 2022 117 trích dẫn

[Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot]. Other

Nutricion hospitalaria 2021 20 trích dẫn

Nutritional interventions for treating foot ulcers in people with diabetes. Meta-Analysis

The Cochrane database … 2020 33 trích dẫn

Nutrition and Wound Healing: An Overview Focusing on the Beneficial Effects of Curcumin. Review

International journal of … 2019 265 trích dẫn

A nutritional formula enriched with arginine, zinc, and antioxidants for the healing of pressure ulcers: a randomized trial. RCT

Annals of internal … 2015 110 trích dẫn

Micronutrient deficiencies in inflammatory bowel disease: from A to zinc. Review

Inflammatory bowel diseases 2012 224 trích dẫn

Efficacy of vitamin supplementation in situations with wound healing disorders: results from clinical intervention studies. Review

Current opinion in … 2009 66 trích dẫn

Dermatologic signs in patients with eating disorders. Review

American journal of … 2005 140 trích dẫn

The use and role of zinc and its compounds in wound healing. Review

Metal ions in … 2004

Zinc supplementation. Other

Journal of the … 2000 52 trích dẫn

Nutrition and wound healing. Review

JPEN. Journal of … 1994 72 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:: 8-11 mg/day (RDA)
acneskinhealth:: 15-30 mg/day

Giới hạn trên: 40 mg/day (elemental zinc — higher doses may cause copper depletion)

Liều lượng đã nghiên cứu

Liều lượng	Thời gian	Hiệu quả	N
None	--	Mixed	--
None	--	Mixed	--
None	--	Positive	--
None	--	Negative	--
SA-Arg-Zn2+ hydrogel	--	Positive	--
None	--	Positive	--
20 g	--	Neutral	629
None	--	Mixed	--

Thời điểm dùng tốt nhất: With meals to reduce nausea; avoid taking with iron or calcium

Safety & Side Effects

Tác dụng phụ đã được báo cáo

⚠ Nausea (especially on empty stomach)
⚠ Copper depletion with long-term high-dose use
⚠ Metallic taste
⚠ Headache

Tương tác đã biết

● Copper supplements (mutual absorption competition — separate by 2+ hours)
● Tetracycline and quinolone antibiotics (reduced antibiotic absorption)
● Penicillamine (reduced absorption of both)
● Iron supplements (competitive absorption)

Mức hấp thụ tối đa cho phép: 40 mg/day (elemental zinc — higher doses may cause copper depletion)

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Zinc help with Wound Healing?

Based on 18 studies with 1,500 participants, there is strong evidence from multiple clinical trials that Zinc may support Wound Healing management. Our evidence grade is A (Strong Evidence).

How much Zinc should I take for Wound Healing?

Studies have used various dosages. A commonly studied range is 8-11 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Zinc?

Reported side effects may include Nausea (especially on empty stomach), Copper depletion with long-term high-dose use, Metallic taste, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Zinc and Wound Healing?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 18 peer-reviewed studies with 1,500 total participants. The overall direction of effect is positive.

Các thành phần khác cho Wound Healing

Aloe Vera D Copper D

Zinc cho các tình trạng khác

Acne A

Đánh giá nhanh

Well-established evidence that zinc is essential for wound healing. Zinc deficiency impairs all phases of repair. Supplementation in deficient individuals may help accelerate wound closure.

Evidence Strength92%

High confidence

Phân tích nghiên cứu

RCT (1)Meta (1)Other (16)

So sánh lựa chọn thay thế

Xem các thành phần khác so sánh như thế nào cho tình trạng này.

Xem tất cả thành phần cho Wound Healing

Tìm hiểu thêm

References

[1] Jialiang Pan et al.. J Colloid Interface Sci. 2025. Glucose-responsive multifunctional hydrogel incorporating GOx@ZIF-8 for NO/Zn2+-mediated antibacterial and pro-angiogenic diabetic wound healing. doi:10.1016/j.jcis.2025.138423 PubMed
[2] Patrick B Wilson et al.. Int J Sport Nutr Exerc Metab. 2025. UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses and Injuries in Elite Cycling. doi:10.1123/ijsnem.2025-0144 PubMed
[3] Anita Horvatić et al.. Metabolites. 2025. Combining Metabolomics and Proteomics to Reveal Key Serum Compounds Related to Canine Intervertebral Disc Herniation. doi:10.3390/metabo15060396 PubMed
[4] Allan Carlos Soares do Espírito Santo et al.. Nutrition. 2024. Impact of oral nutritional supplement composition on healing of different chronic wounds: A systematic review. doi:10.1016/j.nut.2024.112449 PubMed
[5] Ganzhe Mao et al.. Carbohydr Polym. 2023. Preparation and evaluation of a novel alginate-arginine-zinc ion hydrogel film for skin wound healing. doi:10.1016/j.carbpol.2023.120757 PubMed
[6] Yating Yang et al.. Theranostics. 2023. Curcumin-zinc framework encapsulated microneedle patch for promoting hair growth. doi:10.7150/thno.84118 PubMed
[7] Ajay Kumar et al.. Heliyon. 2022. A review on bioactive phytochemicals and ethnopharmacological potential of purslane (Portulaca oleracea L.). doi:10.1016/j.heliyon.2021.e08669 PubMed
[8] Rosa María Martínez García et al.. Nutr Hosp. 2021. [Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot]. doi:10.20960/nh.03800 PubMed
[9] Zena Eh Moore et al.. Cochrane Database Syst Rev. 2020. Nutritional interventions for treating foot ulcers in people with diabetes. doi:10.1002/14651858.CD011378.pub2 PubMed
[10] Martina Barchitta et al.. Int J Mol Sci. 2019. Nutrition and Wound Healing: An Overview Focusing on the Beneficial Effects of Curcumin. doi:10.3390/ijms20051119 PubMed
[11] Emanuele Cereda et al.. Ann Intern Med. 2015. A nutritional formula enriched with arginine, zinc, and antioxidants for the healing of pressure ulcers: a randomized trial. doi:10.7326/M14-0696 PubMed
[12] Caroline Hwang et al.. Inflamm Bowel Dis. 2012. Micronutrient deficiencies in inflammatory bowel disease: from A to zinc. doi:10.1002/ibd.22906 PubMed
[13] Sabine Ellinger et al.. Curr Opin Clin Nutr Metab Care. 2009. Efficacy of vitamin supplementation in situations with wound healing disorders: results from clinical intervention studies. doi:10.1097/MCO.0b013e328331a5b5 PubMed
[14] Renata Strumia. Am J Clin Dermatol. 2005. Dermatologic signs in patients with eating disorders. doi:10.2165/00128071-200506030-00003 PubMed
[15] Paul W Jones et al.. Met Ions Biol Syst. 2004. The use and role of zinc and its compounds in wound healing. PubMed
[16] C J Klein. J Am Diet Assoc. 2000. Zinc supplementation. doi:10.1016/S0002-8223(00)00331-X PubMed
[17] J E Albina. JPEN J Parenter Enteral Nutr. 1994. Nutrition and wound healing. doi:10.1177/014860719401800417 PubMed

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Zinc cho Wound Healing

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Kết luận

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Liều lượng thường dùng

Liều lượng đã nghiên cứu

Safety & Side Effects

Tác dụng phụ đã được báo cáo

Tương tác đã biết

Frequently Asked Questions

Related Evidence

Các thành phần khác cho Wound Healing

Zinc cho các tình trạng khác

References