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Zinc для Wound Healing

A Доказательства Несколько крупных клинических испытаний стабильно демонстрируют значительные преимущества.

Well-established evidence that zinc is essential for wound healing. Zinc deficiency impairs all phases of repair. Supplementation in deficient individuals may help accelerate wound closure.

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A

Итог

Well-established evidence that zinc is essential for wound healing. Zinc deficiency impairs all phases of repair. Supplementation in deficient individuals may help accelerate wound closure.

Key Study Findings

Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None или: None Outcome: None Эффект: None None

Популяция: Elite/professional cyclists nutrition review

Observational Study
Combining Metabolomics and Proteomics to Reveal Key Serum Compounds Related to Canine Intervertebral Disc Herniation.
Dose: None или: None Outcome: None Эффект: None None

Популяция: Dogs with intervertebral disc herniation

In Vitro
Glucose-responsive multifunctional hydrogel incorporating GOx@ZIF-8 for NO/Zn2+-mediated antibacterial and pro-angiogenic diabetic wound healing.
Dose: None или: None Outcome: Diabetic wound healing Эффект: None None

Популяция: Diabetic wound model

Systematic Review
Impact of oral nutritional supplement composition on healing of different chronic wounds: A systematic review.
Dose: None или: Control Outcome: Wound healing Эффект: None None

Популяция: Diabetic patients

In Vitro
Preparation and evaluation of a novel alginate-arginine-zinc ion hydrogel film for skin wound healing.
Dose: SA-Arg-Zn2+ hydrogel или: Other dressing materials Outcome: Wound healing, antibacterial, antioxidant Эффект: None None

Популяция: In vitro + animal wound model

Other
[Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot].
Dose: None или: None Outcome: None Эффект: None None

Популяция: chronic wounds and have been linked to delayed wound healing and dehiscence

Key Statistics

18

Исследования

1500

Участники

Positive

A

Оценка

Referenced Papers

Nutrition (Burbank, Los … 2024 12 цитирований
The Cochrane database … 2020 33 цитирований
International journal of … 2019 265 цитирований
Inflammatory bowel diseases 2012 224 цитирований
American journal of … 2005 140 цитирований
Journal of the … 2000 52 цитирований
JPEN. Journal of … 1994 72 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
8-11 mg/day (RDA)
acneskinhealth:
15-30 mg/day

Верхний предел: 40 mg/day (elemental zinc — higher doses may cause copper depletion)

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
None -- Mixed --
None -- Mixed --
None -- Positive --
None -- Negative --
SA-Arg-Zn2+ hydrogel -- Positive --
None -- Positive --
20 g -- Neutral 629
None -- Mixed --

Лучшее время приёма: With meals to reduce nausea; avoid taking with iron or calcium

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Nausea (especially on empty stomach)
  • Copper depletion with long-term high-dose use
  • Metallic taste
  • Headache

Известные взаимодействия

  • Copper supplements (mutual absorption competition — separate by 2+ hours)
  • Tetracycline and quinolone antibiotics (reduced antibiotic absorption)
  • Penicillamine (reduced absorption of both)
  • Iron supplements (competitive absorption)

Допустимый верхний уровень потребления: 40 mg/day (elemental zinc — higher doses may cause copper depletion)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Zinc help with Wound Healing?
Based on 18 studies with 1,500 participants, there is strong evidence from multiple clinical trials that Zinc may support Wound Healing management. Our evidence grade is A (Strong Evidence).
How much Zinc should I take for Wound Healing?
Studies have used various dosages. A commonly studied range is 8-11 mg/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Zinc?
Reported side effects may include Nausea (especially on empty stomach), Copper depletion with long-term high-dose use, Metallic taste, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Zinc and Wound Healing?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 18 peer-reviewed studies with 1,500 total participants. The overall direction of effect is positive.

Другие ингредиенты для Wound Healing

Zinc для других состояний

References

  1. [1] Jialiang Pan et al.. J Colloid Interface Sci. 2025. Glucose-responsive multifunctional hydrogel incorporating GOx@ZIF-8 for NO/Zn2+-mediated antibacterial and pro-angiogenic diabetic wound healing. doi:10.1016/j.jcis.2025.138423 PubMed
  2. [2] Patrick B Wilson et al.. Int J Sport Nutr Exerc Metab. 2025. UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses and Injuries in Elite Cycling. doi:10.1123/ijsnem.2025-0144 PubMed
  3. [3] Anita Horvatić et al.. Metabolites. 2025. Combining Metabolomics and Proteomics to Reveal Key Serum Compounds Related to Canine Intervertebral Disc Herniation. doi:10.3390/metabo15060396 PubMed
  4. [4] Allan Carlos Soares do Espírito Santo et al.. Nutrition. 2024. Impact of oral nutritional supplement composition on healing of different chronic wounds: A systematic review. doi:10.1016/j.nut.2024.112449 PubMed
  5. [5] Ganzhe Mao et al.. Carbohydr Polym. 2023. Preparation and evaluation of a novel alginate-arginine-zinc ion hydrogel film for skin wound healing. doi:10.1016/j.carbpol.2023.120757 PubMed
  6. [6] Yating Yang et al.. Theranostics. 2023. Curcumin-zinc framework encapsulated microneedle patch for promoting hair growth. doi:10.7150/thno.84118 PubMed
  7. [7] Ajay Kumar et al.. Heliyon. 2022. A review on bioactive phytochemicals and ethnopharmacological potential of purslane (Portulaca oleracea L.). doi:10.1016/j.heliyon.2021.e08669 PubMed
  8. [8] Rosa María Martínez García et al.. Nutr Hosp. 2021. [Nutrition in the prevention and healing of chronic wounds. Importance in improving the diabetic foot]. doi:10.20960/nh.03800 PubMed
  9. [9] Zena Eh Moore et al.. Cochrane Database Syst Rev. 2020. Nutritional interventions for treating foot ulcers in people with diabetes. doi:10.1002/14651858.CD011378.pub2 PubMed
  10. [10] Martina Barchitta et al.. Int J Mol Sci. 2019. Nutrition and Wound Healing: An Overview Focusing on the Beneficial Effects of Curcumin. doi:10.3390/ijms20051119 PubMed
  11. [11] Emanuele Cereda et al.. Ann Intern Med. 2015. A nutritional formula enriched with arginine, zinc, and antioxidants for the healing of pressure ulcers: a randomized trial. doi:10.7326/M14-0696 PubMed
  12. [12] Caroline Hwang et al.. Inflamm Bowel Dis. 2012. Micronutrient deficiencies in inflammatory bowel disease: from A to zinc. doi:10.1002/ibd.22906 PubMed
  13. [13] Sabine Ellinger et al.. Curr Opin Clin Nutr Metab Care. 2009. Efficacy of vitamin supplementation in situations with wound healing disorders: results from clinical intervention studies. doi:10.1097/MCO.0b013e328331a5b5 PubMed
  14. [14] Renata Strumia. Am J Clin Dermatol. 2005. Dermatologic signs in patients with eating disorders. doi:10.2165/00128071-200506030-00003 PubMed
  15. [15] Paul W Jones et al.. Met Ions Biol Syst. 2004. The use and role of zinc and its compounds in wound healing. PubMed
  16. [16] C J Klein. J Am Diet Assoc. 2000. Zinc supplementation. doi:10.1016/S0002-8223(00)00331-X PubMed
  17. [17] J E Albina. JPEN J Parenter Enteral Nutr. 1994. Nutrition and wound healing. doi:10.1177/014860719401800417 PubMed

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