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Omega-3 Fatty Acids для Psoriasis

D Исследования Существуют только предварительные исследования (лабораторные исследования, описания случаев).

Some RCTs suggest omega-3 supplementation may modestly improve psoriasis severity through anti-inflammatory effects, but results are inconsistent across trials.

D

Итог

Some RCTs suggest omega-3 supplementation may modestly improve psoriasis severity through anti-inflammatory effects, but results are inconsistent across trials.

Key Study Findings

Other
In vivo response of GsdmA3(Dfl)/+ mice to topically applied fish oil - effects on cellular …
Dose: 100 mg или: control

Популяция: psoriasis patients

Review
Omega-3 fatty acids and inflammation.
Dose: EPA and DHA Outcome: Anti-inflammatory and immune effects

Популяция: CHD, RA, psoriasis, asthma, IBD patients

Review
Omega-3 fatty acids in inflammation and autoimmune diseases.
Dose: Omega-3 fatty acids (EPA, DHA) Outcome: Inflammation and autoimmune disease modulation

Популяция: RA, Crohn's, UC, lupus patients

Review
Omega-3 fatty acids in health and disease and in growth and development.
Dose: 32 g Outcome: lipid levels

Популяция: cancer patients

Key Statistics

6

Исследования

400

Участники

↑

Positive

D

Оценка

Referenced Papers

Journal of cosmetic … 2022 30 цитирований
Clinics in dermatology 2016 19 цитирований
Journal of the … 2014 93 цитирований
Current atherosclerosis reports 2004 464 цитирований
Journal of the … 2002 2016 цитирований
Drugs 1998 99 цитирований
Arquivos de gastroenterologia 1996
The American journal … 1991 2278 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
250-500 mg combined EPA/DHA per day
skinhealth:
1,000-2,000 mg/day EPA+DHA

Верхний предел: 3,000 mg/day combined EPA/DHA (FDA GRAS)

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
100 mg -- Mixed --
EPA and DHA -- Positive --
Omega-3 fatty acids (EPA, DHA) -- Positive --
32 g -- Mixed --

Лучшее время приёма: With meals containing fat for better absorption

Safety & Side Effects

Зарегистрированные побочные эффекты

  • ⚠ Fishy aftertaste or burping
  • ⚠ Mild gastrointestinal discomfort
  • ⚠ Potential increased bleeding time at very high doses
  • ⚠ May lower blood pressure slightly

Известные взаимодействия

  • ● Anticoagulants and antiplatelet drugs (may increase bleeding risk at high doses)
  • ● Blood pressure medications (additive hypotensive effect)
  • ● Orlistat (may reduce omega-3 absorption)

Допустимый верхний уровень потребления: 3,000 mg/day combined EPA/DHA (FDA GRAS)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Omega-3 Fatty Acids help with Psoriasis?
Based on 6 studies with 400 participants, there is preliminary evidence that needs more research that Omega-3 Fatty Acids may support Psoriasis management. Our evidence grade is D (Very Early Research).
How much Omega-3 Fatty Acids should I take for Psoriasis?
Studies have used various dosages. A commonly studied range is 250-500 mg combined EPA/DHA per day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Omega-3 Fatty Acids?
Reported side effects may include Fishy aftertaste or burping, Mild gastrointestinal discomfort, Potential increased bleeding time at very high doses, May lower blood pressure slightly. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Omega-3 Fatty Acids and Psoriasis?
We rate the evidence as Grade D (Very Early Research). This rating is based on 6 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Другие ингредиенты для Psoriasis

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References

  1. [1] Ada Radu et al.. Inflammopharmacology. 2025. Naturally derived bioactive compounds as precision modulators of immune and inflammatory mechanisms in psoriatic conditions. doi:10.1007/s10787-024-01602-z PubMed
  2. [2] Luigi Barrea et al.. Curr Obes Rep. 2025. Medical Nutrition Therapy in Dermatological Diseases: A Joint Consensus Statement of the Italian Association of Dietetics and Clinical Nutrition (ADI), … doi:10.1007/s13679-025-00630-2 PubMed
  3. [3] Kimsor Hong et al.. Autoimmun Rev. 2024. Association between Omega-3 fatty acids and autoimmune disease: Evidence from the umbrella review and Mendelian randomization analysis. doi:10.1016/j.autrev.2024.103651 PubMed
  4. [4] Kabir Sardana et al.. J Cosmet Dermatol. 2022. Role of nutritional supplements in selected dermatological disorders: A review. doi:10.1111/jocd.14436 PubMed
  5. [5] Meagen McCusker et al.. Clin Dermatol. 2016. Nutrition and skin: Kids are not just little people. doi:10.1016/j.clindermatol.2016.07.004 PubMed
  6. [6] Mohd Hanif Zulfakar et al.. FEBS Open Bio. 2016. In vivo response of GsdmA3(Dfl)/+ mice to topically applied fish oil - effects on cellular markers and macrophages. doi:10.1002/2211-5463.12095 PubMed
  7. [7] Jillian W Millsop et al.. J Am Acad Dermatol. 2014. Diet and psoriasis, part III: role of nutritional supplements. doi:10.1016/j.jaad.2014.03.016 PubMed
  8. [8] Trevor A Mori et al.. Curr Atheroscler Rep. 2004. Omega-3 fatty acids and inflammation. doi:10.1007/s11883-004-0087-5 PubMed
  9. [9] Artemis P Simopoulos. J Am Coll Nutr. 2002. Omega-3 fatty acids in inflammation and autoimmune diseases. doi:10.1080/07315724.2002.10719248 PubMed
  10. [10] A Heller et al.. Drugs. 1998. Lipid mediators in inflammatory disorders. doi:10.2165/00003495-199855040-00001 PubMed
  11. [11] C Cukier et al.. Arq Gastroenterol. 1996. [Biological activity of fish oil]. PubMed
  12. [12] A P Simopoulos. Am J Clin Nutr. 1991. Omega-3 fatty acids in health and disease and in growth and development. doi:10.1093/ajcn/54.3.438 PubMed

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