Omega-3 Fatty Acids для Psoriasis

D Исследования Существуют только предварительные исследования (лабораторные исследования, описания случаев).

Some RCTs suggest omega-3 supplementation may modestly improve psoriasis severity through anti-inflammatory effects, but results are inconsistent across trials.

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Итог

Some RCTs suggest omega-3 supplementation may modestly improve psoriasis severity through anti-inflammatory effects, but results are inconsistent across trials.

Key Study Findings

Review

Naturally derived bioactive compounds as precision modulators of immune and inflammatory mechanisms in psoriatic conditions.

Dose: None или: None Outcome: None Эффект: None None

Популяция: review of naturally derived bioactive compounds for psoriasis (flavonoids, terpenoids, omega-3, alkaloids)

Review

Medical Nutrition Therapy in Dermatological Diseases: A Joint Consensus Statement of the Italian Association of …

Dose: None или: None Outcome: None Эффект: None None

Популяция: Patients with acne, HS, or psoriasis

Review

Association between Omega-3 fatty acids and autoimmune disease: Evidence from the umbrella review and Mendelian …

Dose: None или: None Outcome: Colitis severity Эффект: None None

Популяция: Crohn's disease patients

narrative_review

Nutrition and skin: Kids are not just little people.

Dose: None или: Placebo Эффект: narrative review; discusses role of nutrition from prenatal period on skin immune responses; highlig not_applicable

Other

In vivo response of GsdmA3(Dfl)/+ mice to topically applied fish oil - effects on cellular …

Dose: 100 mg или: control Outcome: None Эффект: None None

Популяция: psoriasis patients

Review

Diet and psoriasis, part III: role of nutritional supplements.

Dose: None или: None Outcome: None Эффект: None None

Популяция: psoriasis patients

Key Statistics

Исследования

400

Участники

↑

Positive

Оценка

Referenced Papers

Naturally derived bioactive compounds as precision modulators of immune and inflammatory mechanisms in psoriatic conditions. Review

Inflammopharmacology 2025 26 цитирований

Medical Nutrition Therapy in Dermatological Diseases: A Joint Consensus Statement of the Italian Association of Dietetics and Clinical Nutrition (ADI), … Review

Current obesity reports 2025

Association between Omega-3 fatty acids and autoimmune disease: Evidence from the umbrella review and Mendelian randomization analysis. Review

Autoimmunity reviews 2024 12 цитирований

Role of nutritional supplements in selected dermatological disorders: A review. Review

Journal of cosmetic … 2022 30 цитирований

Nutrition and skin: Kids are not just little people. Review

Clinics in dermatology 2016 19 цитирований

In vivo response of GsdmA3(Dfl)/+ mice to topically applied fish oil - effects on cellular markers and macrophages. Other

FEBS open bio 2016 1 цитирований

Diet and psoriasis, part III: role of nutritional supplements. Review

Journal of the … 2014 93 цитирований

Omega-3 fatty acids and inflammation. Review

Current atherosclerosis reports 2004 464 цитирований

Omega-3 fatty acids in inflammation and autoimmune diseases. Review

Journal of the … 2002 2016 цитирований

Lipid mediators in inflammatory disorders. Review

Drugs 1998 99 цитирований

[Biological activity of fish oil]. Review

Arquivos de gastroenterologia 1996

Omega-3 fatty acids in health and disease and in growth and development. Review

The American journal … 1991 2278 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:: 250-500 mg combined EPA/DHA per day
skinhealth:: 1,000-2,000 mg/day EPA+DHA

Верхний предел: 3,000 mg/day combined EPA/DHA (FDA GRAS)

Дозировки, изученные в исследованиях

Дозировка	Длительность	Эффект	N
None	--	Positive	--
None	--	Mixed	--
None	--	Neutral	--
None	--	Positive	--
100 mg	--	Mixed	--
None	--	Positive	--
EPA and DHA	--	Positive	--
Omega-3 fatty acids (EPA, DHA)	--	Positive	--

Лучшее время приёма: With meals containing fat for better absorption

Safety & Side Effects

Зарегистрированные побочные эффекты

⚠ Fishy aftertaste or burping
⚠ Mild gastrointestinal discomfort
⚠ Potential increased bleeding time at very high doses
⚠ May lower blood pressure slightly

Известные взаимодействия

● Anticoagulants and antiplatelet drugs (may increase bleeding risk at high doses)
● Blood pressure medications (additive hypotensive effect)
● Orlistat (may reduce omega-3 absorption)

Допустимый верхний уровень потребления: 3,000 mg/day combined EPA/DHA (FDA GRAS)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Omega-3 Fatty Acids help with Psoriasis?

Based on 6 studies with 400 participants, there is preliminary evidence that needs more research that Omega-3 Fatty Acids may support Psoriasis management. Our evidence grade is D (Very Early Research).

How much Omega-3 Fatty Acids should I take for Psoriasis?

Studies have used various dosages. A commonly studied range is 250-500 mg combined EPA/DHA per day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Omega-3 Fatty Acids?

Reported side effects may include Fishy aftertaste or burping, Mild gastrointestinal discomfort, Potential increased bleeding time at very high doses, May lower blood pressure slightly. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Omega-3 Fatty Acids and Psoriasis?

We rate the evidence as Grade D (Very Early Research). This rating is based on 6 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Другие ингредиенты для Psoriasis

Vitamin D B Turmeric (Curcumin) C

Omega-3 Fatty Acids для других состояний

Eczema (Atopic Dermatitis) B UV Protection (Internal Photoprotection) B Acne C Rosacea C

Краткий вывод

Some RCTs suggest omega-3 supplementation may modestly improve psoriasis severity through anti-inflammatory effects, but results are inconsistent across trials.

Evidence Strength30%

Low confidence

Разбор исследований

RCT (0)Meta (0)Other (6)

Сравнить альтернативы

Узнайте, как другие ингредиенты сравниваются при данном состоянии.

Посмотреть все ингредиенты для Psoriasis

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References

[1] Ada Radu et al.. Inflammopharmacology. 2025. Naturally derived bioactive compounds as precision modulators of immune and inflammatory mechanisms in psoriatic conditions. doi:10.1007/s10787-024-01602-z PubMed
[2] Luigi Barrea et al.. Curr Obes Rep. 2025. Medical Nutrition Therapy in Dermatological Diseases: A Joint Consensus Statement of the Italian Association of Dietetics and Clinical Nutrition (ADI), … doi:10.1007/s13679-025-00630-2 PubMed
[3] Kimsor Hong et al.. Autoimmun Rev. 2024. Association between Omega-3 fatty acids and autoimmune disease: Evidence from the umbrella review and Mendelian randomization analysis. doi:10.1016/j.autrev.2024.103651 PubMed
[4] Kabir Sardana et al.. J Cosmet Dermatol. 2022. Role of nutritional supplements in selected dermatological disorders: A review. doi:10.1111/jocd.14436 PubMed
[5] Meagen McCusker et al.. Clin Dermatol. 2016. Nutrition and skin: Kids are not just little people. doi:10.1016/j.clindermatol.2016.07.004 PubMed
[6] Mohd Hanif Zulfakar et al.. FEBS Open Bio. 2016. In vivo response of GsdmA3(Dfl)/+ mice to topically applied fish oil - effects on cellular markers and macrophages. doi:10.1002/2211-5463.12095 PubMed
[7] Jillian W Millsop et al.. J Am Acad Dermatol. 2014. Diet and psoriasis, part III: role of nutritional supplements. doi:10.1016/j.jaad.2014.03.016 PubMed
[8] Trevor A Mori et al.. Curr Atheroscler Rep. 2004. Omega-3 fatty acids and inflammation. doi:10.1007/s11883-004-0087-5 PubMed
[9] Artemis P Simopoulos. J Am Coll Nutr. 2002. Omega-3 fatty acids in inflammation and autoimmune diseases. doi:10.1080/07315724.2002.10719248 PubMed
[10] A Heller et al.. Drugs. 1998. Lipid mediators in inflammatory disorders. doi:10.2165/00003495-199855040-00001 PubMed
[11] C Cukier et al.. Arq Gastroenterol. 1996. [Biological activity of fish oil]. PubMed
[12] A P Simopoulos. Am J Clin Nutr. 1991. Omega-3 fatty acids in health and disease and in growth and development. doi:10.1093/ajcn/54.3.438 PubMed

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Omega-3 Fatty Acids для Psoriasis

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Итог

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Часто используемые дозировки

Дозировки, изученные в исследованиях

Safety & Side Effects

Зарегистрированные побочные эффекты

Известные взаимодействия

Frequently Asked Questions

Related Evidence

Другие ингредиенты для Psoriasis

Omega-3 Fatty Acids для других состояний

References