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Omega-3 Fatty Acids для Acne

C Доказательства Доказательства ограничены небольшими исследованиями, однако имеются некоторые положительные сигналы.

Research suggests omega-3 supplementation may reduce inflammatory acne lesions through anti-inflammatory eicosanoid modulation (reduced PGE2 and LTB4 production).

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Итог

Research suggests omega-3 supplementation may reduce inflammatory acne lesions through anti-inflammatory eicosanoid modulation (reduced PGE2 and LTB4 production).

Key Study Findings

Review
Medical Nutrition Therapy in Dermatological Diseases: A Joint Consensus Statement of the Italian Association of …
Dose: None или: None Outcome: None Эффект: None None

Популяция: Patients with acne, HS, or psoriasis

narrative_review
Nutrition and skin: Kids are not just little people.
Dose: None или: Placebo Эффект: narrative review; discusses role of nutrition from prenatal period on skin immune responses; highlig not_applicable

Key Statistics

5

Исследования

300

Участники

Positive

C

Оценка

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
250-500 mg combined EPA/DHA per day
skinhealth:
1,000-2,000 mg/day EPA+DHA

Верхний предел: 3,000 mg/day combined EPA/DHA (FDA GRAS)

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
None -- Mixed --
None -- Positive --

Лучшее время приёма: With meals containing fat for better absorption

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Fishy aftertaste or burping
  • Mild gastrointestinal discomfort
  • Potential increased bleeding time at very high doses
  • May lower blood pressure slightly

Известные взаимодействия

  • Anticoagulants and antiplatelet drugs (may increase bleeding risk at high doses)
  • Blood pressure medications (additive hypotensive effect)
  • Orlistat (may reduce omega-3 absorption)

Допустимый верхний уровень потребления: 3,000 mg/day combined EPA/DHA (FDA GRAS)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Omega-3 Fatty Acids help with Acne?
Based on 5 studies with 300 participants, there is limited but promising evidence that Omega-3 Fatty Acids may support Acne management. Our evidence grade is C (Some Evidence).
How much Omega-3 Fatty Acids should I take for Acne?
Studies have used various dosages. A commonly studied range is 250-500 mg combined EPA/DHA per day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Omega-3 Fatty Acids?
Reported side effects may include Fishy aftertaste or burping, Mild gastrointestinal discomfort, Potential increased bleeding time at very high doses, May lower blood pressure slightly. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Omega-3 Fatty Acids and Acne?
We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.

References

  1. [1] Luigi Barrea et al.. Curr Obes Rep. 2025. Medical Nutrition Therapy in Dermatological Diseases: A Joint Consensus Statement of the Italian Association of Dietetics and Clinical Nutrition (ADI), … doi:10.1007/s13679-025-00630-2 PubMed
  2. [2] Kabir Sardana et al.. J Cosmet Dermatol. 2022. Role of nutritional supplements in selected dermatological disorders: A review. doi:10.1111/jocd.14436 PubMed
  3. [3] Meagen McCusker et al.. Clin Dermatol. 2016. Nutrition and skin: Kids are not just little people. doi:10.1016/j.clindermatol.2016.07.004 PubMed

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