What is the recommended dosage for Resveratrol?

General: 150-500 mg/day; Skin Health: 250-500 mg/day trans-resveratrol

What are the side effects of Resveratrol?

Potential side effects include: Gastrointestinal discomfort at high doses, Diarrhea, May affect platelet aggregation.

What is resveratrol and how may it support skin health?

Resveratrol is a polyphenol found in grape skins and red wine with antioxidant and anti-inflammatory properties. It activates sirtuins (SIRT1) involved in cellular repair and longevity pathways. Some clinical studies suggest oral resveratrol may improve skin hydration, elasticity, and reduce hyperpigmentation.

What dosage of resveratrol has been studied for skin benefits?

Skin-related studies have used 25–250 mg of resveratrol per day for 4–12 weeks. Due to low oral bioavailability, higher doses or enhanced formulations may be needed. Trans-resveratrol is the more biologically active isomer. Studies often combined resveratrol with other antioxidants.

What are the potential side effects of resveratrol?

Common side effects include gastrointestinal discomfort, nausea, and diarrhea at higher doses. Resveratrol may have estrogenic activity. It can interact with blood thinners and drugs metabolized by CYP enzymes. Long-term safety at supplemental doses is not well established in humans.

Resveratrol
Resveratrol

antioxidant

다른 이름: trans-Resveratrol, 3,5,4'-Trihydroxystilbene

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About

Resveratrol is a polyphenol stilbene that activates SIRT1 longevity pathways and inhibits tyrosinase to reduce melanogenesis. In vitro evidence is strong, but oral bioavailability is extremely low (< 2%). A small RCT found 250 mg/day for 60 days improved skin smoothness and reduced hyperpigmentation.

How It Works

Polyphenol stilbene that activates SIRT1 (sirtuin 1) longevity pathways; inhibits tyrosinase to reduce melanogenesis; suppresses NF-kB and COX-2 inflammatory cascades; may protect against UV-induced DNA damage and MMP expression.

Evidence For Conditions

건강 상태	등급	연구	참여자
Aging Skin & Wrinkles	C	4	200	보기 →

Side Effects

Gastrointestinal discomfort at high doses
Diarrhea
May affect platelet aggregation

Drug & Supplement Interactions

Anticoagulants (may have antiplatelet effects)
CYP450 substrates (may inhibit drug metabolism)
Estrogen-sensitive conditions (has weak estrogenic activity)

복용 중인 모든 건강기능식품에 대해 반드시 의료 전문가에게 알리십시오.

Related Ingredients

Astaxanthin Glutathione CoQ10 Alpha-Lipoic Acid

핵심 정보

용량: General: 150-500 mg/day; Skin_Health: 250-500 mg/day trans-resveratrol
제형: capsule tablet liquid powder
천연 원료: Red grapes, Red wine, Peanuts, Blueberries, Cranberries, Japanese knotweed (Polygonum cuspidatum)
상한 섭취량: Generally well-tolerated up to 1,500 mg/day; GI discomfort above 2,500 mg/day
권장 복용 시간: With meals for improved absorption; low oral bioavailability (~1-2%)

근거 요약

Aging Skin & Wrinkles C

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.