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Nicotinamide 관련 UV Protection (Internal Photoprotection)

A

At chemoprevention doses (1,000 mg/day), oral nicotinamide replenishes UV-depleted NAD+ stores, enhancing cellular energy for DNA repair and supporting immune surveillance of UV-damaged cells (ONTRAC Phase 3 trial).

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            A

        

        

            
결론

            
            
At chemoprevention doses (1,000 mg/day), oral nicotinamide replenishes UV-depleted NAD+ stores, enhancing cellular energy for DNA repair and supporting immune surveillance of UV-damaged cells (ONTRAC Phase 3 trial).

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
5

        
연구

    

    

        
686

        
참여자

    

    

        
            
            ↑
            
        
        
Positive

    

    

        A

        
등급

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
일반적으로 사용되는 용량

                

                    
                    

                        
generalskinbarrier:

                        
500-1,500 mg/day

                    

                    
                    

                        
skincancerchemoprevention:

                        
500 mg twice daily (1,000 mg/day total)

                    

                    
                

                
                

                    상한량: Generally well-tolerated up to 3,000 mg/day (no flushing unlike niacin)
                

                
            

            

            

            
            

                권장 복용 시간: With meals; split into 2 doses for chemoprevention
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
보고된 부작용

                    
    
                        
                        
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                            ⚠
                            Generally well-tolerated (no flushing)
                        
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                            ⚠
                            Mild gastrointestinal discomfort at high doses
                        
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                            ⚠
                            Rare hepatotoxicity at very high doses
                        
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알려진 상호작용

                    
    
                        
                        
  • 
                            ●
                            Anticonvulsants (carbamazepine — may increase levels)
                        
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                            Isoniazid (competes for NAD+ pathways)
                        
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                            Hepatotoxic drugs (potential additive liver effect at high doses)
                        
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                        일일 최대 섭취 허용량: Generally well-tolerated up to 3,000 mg/day (no flushing unlike niacin)
                    

                

                
            

            

                건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Nicotinamide help with UV Protection (Internal Photoprotection)?
            
        
        

            Based on 5 studies with 686 participants, there is strong evidence from multiple clinical trials that Nicotinamide may support UV Protection (Internal Photoprotection) management. Our evidence grade is A (Strong Evidence).
        

    

    
    

        
            How much Nicotinamide should I take for UV Protection (Internal Photoprotection)?
            
        
        

            Studies have used various dosages. A commonly studied range is 500-1,500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Nicotinamide?
            
        
        

            Reported side effects may include Generally well-tolerated (no flushing), Mild gastrointestinal discomfort at high doses, Rare hepatotoxicity at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Nicotinamide and UV Protection (Internal Photoprotection)?
            
        
        

            We rate the evidence as Grade A (Strong Evidence). This rating is based on 5 peer-reviewed studies with 686 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

        FDA 면책 조항:
        이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.