An RCT found grape seed extract improved melanin index in women with chloasma. OPCs may inhibit tyrosinase activity and reduce melanogenesis. Limited evidence.
An RCT found grape seed extract improved melanin index in women with chloasma. OPCs may inhibit tyrosinase activity and reduce melanogenesis. Limited evidence.
Key Statistics
3
연구
180
참여자
↑
Positive
C
등급
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
general:
100-300 mg/day
skinhealth:
100-400 mg/day standardized to 95% OPCs
상한량: Generally well-tolerated up to 600 mg/day
권장 복용 시간: With or without food; well absorbed
Safety & Side Effects
보고된 부작용
⚠
Mild gastrointestinal discomfort
⚠
Headache (rare)
⚠
Dizziness (rare)
알려진 상호작용
●
Anticoagulants (may have antiplatelet effects)
●
NSAIDs (may have additive effects)
●
Iron supplements (tannins may reduce absorption)
일일 최대 섭취 허용량: Generally well-tolerated up to 600 mg/day
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Grape Seed Extract help with Hyperpigmentation?
Based on 3 studies with 180 participants, there is limited but promising evidence that Grape Seed Extract may support Hyperpigmentation management. Our evidence grade is C (Some Evidence).
How much Grape Seed Extract should I take for Hyperpigmentation?
Studies have used various dosages. A commonly studied range is 100-300 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Grape Seed Extract?
Reported side effects may include Mild gastrointestinal discomfort, Headache (rare), Dizziness (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Grape Seed Extract and Hyperpigmentation?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 180 total participants. The overall direction of effect is positive.
FDA 면책 조항:
이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.