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Polypodium leucotomos ： UV Protection (Internal Photoprotection)

B

A systematic review found oral PLE significantly increased MED by 1.5-2.8x. The American Academy of Dermatology has acknowledged PLE as a potential adjunct to topical sunscreen.

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            B

        

        

            
結論

            
            
A systematic review found oral PLE significantly increased MED by 1.5-2.8x. The American Academy of Dermatology has acknowledged PLE as a potential adjunct to topical sunscreen.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
5

        
研究数

    

    

        
250

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
グレード

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
240-480 mg/day

                    

                    
                    

                        
photoprotection:

                        
480 mg/day (240 mg twice daily, 30-60 min before sun exposure)

                    

                    
                

                
                

                    上限量： Generally well-tolerated up to 960 mg/day
                

                
            

            

            

            
            

                推奨摂取タイミング： 30-60 minutes before sun exposure; can also be taken daily for baseline protection
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Pruritus (rare)
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Immunosuppressants (may modulate immune function)
                        
    • 
                        
                        
  • 
                            ●
                            Photosensitizing medications (may modulate UV response)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： Generally well-tolerated up to 960 mg/day
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Polypodium leucotomos help with UV Protection (Internal Photoprotection)?
            
        
        

            Based on 5 studies with 250 participants, there is moderate evidence from clinical studies that Polypodium leucotomos may support UV Protection (Internal Photoprotection) management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Polypodium leucotomos should I take for UV Protection (Internal Photoprotection)?
            
        
        

            Studies have used various dosages. A commonly studied range is 240-480 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Polypodium leucotomos?
            
        
        

            Reported side effects may include Generally well-tolerated, Mild gastrointestinal discomfort (rare), Pruritus (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Polypodium leucotomos and UV Protection (Internal Photoprotection)?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 250 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Polypodium leucotomos 他の症状・状態について

                    

                        
                        
                            Hyperpigmentation
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。