HyperpigmentationHyperpigmentation
Hyperpigmentation
Hyperpigmentation
有病率: Melasma affects 15-50% of pregnant women; PIH common in darker skin tones (Fitzpatrick IV-VI)
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Evidence-Ranked Ingredients
| 成分 | グレード | 研究数 | 効果の方向 | |
|---|---|---|---|---|
| Glutathione | C | 6 | Positive | 詳細を見る → |
| Pine Bark Extract (Pycnogenol) | C | 4 | Positive | 詳細を見る → |
| Polypodium leucotomos | C | 3 | Positive | 詳細を見る → |
| Grape Seed Extract | C | 3 | Positive | 詳細を見る → |
| N-Acetyl Cysteine | C | 3 | Positive | 詳細を見る → |
About
Excess melanin deposition in the epidermis or dermis, resulting in darkened patches. Major subtypes include melasma (hormonally driven), post-inflammatory hyperpigmentation (PIH), and solar lentigines (sun spots). Involves upregulation of tyrosinase and melanosome transfer to keratinocytes.
Common Symptoms
Dark patches on face (melasma: cheeks, forehead, upper lip)
Dark spots at sites of prior acne or injury (PIH)
Age spots (solar lentigines)
Uneven skin tone
Risk Factors
- Sun exposure
- Hormonal changes (pregnancy, oral contraceptives)
- Skin inflammation or injury
- Darker skin tones
- Family history
- Certain medications
Frequently Asked Questions
What supplements are studied for Hyperpigmentation?
Research has examined 5 supplement ingredients for Hyperpigmentation, including Glutathione. Evidence strength varies; review individual grades for details.
How is the evidence for Hyperpigmentation supplements graded?
We grade supplements on an A-F scale based on clinical study quality, consistency of results, sample sizes, and study design. Grade A indicates strong evidence from multiple clinical trials, while Grade D indicates preliminary evidence requiring further research.
How many studies on Hyperpigmentation supplements have been reviewed?
Our evidence grades for Hyperpigmentation are based on a total of 19 peer-reviewed studies across 5 ingredients. Studies are sourced from PubMed and include randomized controlled trials, meta-analyses, and other clinical research.
What are common symptoms of Hyperpigmentation?
Common symptoms associated with Hyperpigmentation include Dark patches on face (melasma: cheeks, forehead, upper lip), Dark spots at sites of prior acne or injury (PIH), Age spots (solar lentigines), Uneven skin tone. If you are experiencing these symptoms, consult a healthcare professional for proper diagnosis and treatment options.
Related Conditions
共通の研究済み成分を持つ症状
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