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MSM per Aging Skin & Wrinkles

C Evidenze Evidenza limitata da studi di piccole dimensioni, ma esistono alcuni segnali positivi.

A clinical trial found MSM (3,000 mg/day for 16 weeks) improved skin texture and firmness. MSM provides sulfur for disulfide bonds in collagen, elastin, and keratin.

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A clinical trial found MSM (3,000 mg/day for 16 weeks) improved skin texture and firmness. MSM provides sulfur for disulfide bonds in collagen, elastin, and keratin.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Randomized Controlled Trial
                
                
                n=83
                
                
                16 weeks
                
                
                Double-blind
                
            

            
                Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing.
            
            

                
                Dose: 1 g/d or 3 g/d
                
                
                vs: Placebo (Part I); 1g vs 3g dose (Part II)
                
                
                Outcome: Facial wrinkles, skin firmness, elasticity, hydration
                
                
                Effetto: None
                
                
                p<0.05
                
            

            
            
Popolazione: Healthy adults with signs of skin aging

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
3

        
Studi

    

    

        
180

        
Partecipanti

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Grado

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        International journal for …
                        2022
                        
                        10 citazioni
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosaggi di uso comune

                

                    
                    

                        
general:

                        
1,000-3,000 mg/day

                    

                    
                    

                        
skinhealth:

                        
1,000-3,000 mg/day

                    

                    
                

                
                

                    Limite massimo: Generally well-tolerated up to 6,000 mg/day
                

                
            

            

            
            

                
Dosaggi studiati nella ricerca

                

                    

                        
                            

                                Dosaggio
                                Durata
                                Effetto
                                N
                            

                        
                        
                            
                            

                                1 g/d or 3 g/d
                                16 weeks
                                
                                    
                                    Positive
                                    
                                
                                83
                            

                            
                        
                    

                

            

            

            
            

                Momento migliore per l'assunzione: With meals; can be split into 2-3 doses
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Effetti collaterali segnalati

                    
    
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Insomnia (rare)
                        
    • 
                        
                    

                

                

                
                

                    
Interazioni note

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (theoretical interaction)
                        
    • 
                        
                        
  • 
                            ●
                            Generally considered safe with minimal drug interactions
                        
    • 
                        
                    

                

                

                
                

                    

                        Livello di assunzione massimo tollerabile: Generally well-tolerated up to 6,000 mg/day
                    

                

                
            

            

                Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does MSM help with Aging Skin & Wrinkles?
            
        
        

            Based on 3 studies with 180 participants, there is limited but promising evidence that MSM may support Aging Skin & Wrinkles management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much MSM should I take for Aging Skin & Wrinkles?
            
        
        

            Studies have used various dosages. A commonly studied range is 1,000-3,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of MSM?
            
        
        

            Reported side effects may include Mild gastrointestinal discomfort, Headache (rare), Insomnia (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for MSM and Aging Skin & Wrinkles?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 180 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Neelam Muizzuddin et al..
      Int J Vitam Nutr Res.
      2022.
      Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing.
      doi:10.1024/0300-9831/a000643
      PubMed
    
    2. 
    
  















    

        Avvertenza FDA:
        Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.