What is the recommended dosage for Vitamin D?

General: 600-800 IU/day (RDA); Skin Health: 1,000-4,000 IU/day (targeting 30-50 ng/mL serum 25(OH)D)

What are the side effects of Vitamin D?

Potential side effects include: Generally well-tolerated at recommended doses, Hypercalcemia at very high doses (nausea, vomiting, weakness), Kidney stones (rare, at excessive doses).

What is vitamin D and how may it relate to skin health?

Vitamin D plays roles in skin cell growth, differentiation, and immune function in the skin. Vitamin D receptors are present in keratinocytes. Low vitamin D levels have been associated with several skin conditions including psoriasis, atopic dermatitis, and vitiligo. Vitamin D analogs are used topically in psoriasis treatment.

What dosage of vitamin D has been studied for skin conditions?

Clinical studies for skin conditions have used 1,000–4,000 IU of vitamin D3 per day. Psoriasis studies have used up to 35,000 IU daily under close medical supervision (risk of hypercalcemia). For general skin health, maintaining adequate blood levels (30–50 ng/mL of 25-OH-D) through standard supplementation is recommended.

What are the potential side effects of vitamin D supplements?

Vitamin D is safe at recommended doses but excessive intake causes hypercalcemia with symptoms including nausea, weakness, confusion, and kidney damage. The tolerable upper intake level is 4,000 IU daily for adults, though some experts support higher levels under monitoring. Vitamin D3 is preferred over D2 for supplementation.

Vitamin D
Vitamin D

vitamin

Aussi connu sous le nom de: Cholecalciferol (D3), Ergocalciferol (D2), Calciferol, Sunshine Vitamin

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About

Vitamin D is a secosteroid hormone produced in skin via UVB exposure that regulates keratinocyte differentiation, supports antimicrobial peptide production (cathelicidin), modulates immune responses, and supports wound healing. A systematic review found vitamin D deficiency is significantly associated with increased severity of atopic dermatitis, psoriasis, and vitiligo.

How It Works

Secosteroid hormone produced in skin via UVB exposure; regulates keratinocyte differentiation, supports antimicrobial peptide (cathelicidin) production, modulates immune responses in skin, and supports wound healing through calcium-dependent signaling.

Evidence For Conditions

Pathologie	Note	Études	Participants
Psoriasis	B	16	2200	Voir →
Eczema (Atopic Dermatitis)	B	12	1800	Voir →
Vitiligo	D	4	300	Voir →

Side Effects

Generally well-tolerated at recommended doses
Hypercalcemia at very high doses (nausea, vomiting, weakness)
Kidney stones (rare, at excessive doses)

Drug & Supplement Interactions

Thiazide diuretics (may increase calcium levels)
Corticosteroids (may reduce vitamin D absorption)
Orlistat and cholestyramine (reduce absorption of fat-soluble vitamins)
Calcipotriene (additive vitamin D effect)

Informez toujours votre professionnel de santé de tous les compléments alimentaires que vous prenez.Informez toujours votre professionnel de santé de tous les compléments que vous prenez.

Related Ingredients

Vitamin C Vitamin E Vitamin A (Retinol) Biotin Niacinamide

En bref

Posologie: General: 600-800 IU/day (RDA); Skin_Health: 1,000-4,000 IU/day (targeting 30-50 ng/mL serum 25(OH)D)
Formes: softgel capsule liquid drops gummy tablet
Sources naturelles: Sunlight (UVB radiation), Fatty fish, Egg yolks, Fortified milk, Mushrooms (UV-exposed)
Limite supérieure: 4,000 IU/day (IOM); many experts consider up to 10,000 IU/day safe
Meilleur moment: With meals containing fat for better absorption

Synthèse des preuves

Psoriasis B

Eczema (Atopic Dermatitis) B

Vitiligo D

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.

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