What is the recommended dosage for Grape Seed Extract?

General: 100-300 mg/day; Skin Health: 100-400 mg/day standardized to 95% OPCs

What are the side effects of Grape Seed Extract?

Potential side effects include: Mild gastrointestinal discomfort, Headache (rare), Dizziness (rare).

What is grape seed extract and how may it support skin health?

Grape seed extract contains oligomeric proanthocyanidins (OPCs) with strong antioxidant activity. It may protect collagen and elastin from enzymatic degradation, improve microcirculation in the skin, and reduce UV-induced oxidative damage. Some clinical trials show benefits for skin elasticity, hyperpigmentation, and wound healing.

What dosage of grape seed extract has been studied for skin benefits?

Skin-related studies have used 100–400 mg of grape seed extract per day, standardized to 80–95% OPCs. Improvements in skin elasticity and melanin index were observed at 200 mg daily for 6–12 months. Chloasma (melasma) studies used 200 mg daily. Higher OPC standardization may correlate with greater efficacy.

What are the potential side effects of grape seed extract?

Grape seed extract is generally well tolerated. Mild side effects include headache, digestive discomfort, and sore throat. It may increase bleeding risk when combined with anticoagulants or antiplatelet drugs. Individuals with grape allergies should avoid this supplement. No serious adverse events have been reported in skin studies.

Grape Seed Extract
Grape Seed Extract

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다른 이름: OPC, Oligomeric Proanthocyanidins, Vitis vinifera Extract, GSE

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About

Grape seed extract is a rich source of oligomeric proanthocyanidins (OPCs) that bind and stabilize collagen and elastin fibers with 20x the antioxidant capacity of vitamin C. An RCT found grape seed extract improved skin elasticity and melanin index in women with chloasma after 6 months.

How It Works

Rich source of oligomeric proanthocyanidins (OPCs) that bind and stabilize collagen and elastin fibers; potent free radical scavenger with 20x antioxidant capacity of vitamin C and 50x of vitamin E; may inhibit UV-induced MMP expression and support microvascular integrity in skin.

Evidence For Conditions

건강 상태	등급	연구	참여자
Aging Skin & Wrinkles	C	5	280	보기 →
Hyperpigmentation	C	3	180	보기 →

Side Effects

Mild gastrointestinal discomfort
Headache (rare)
Dizziness (rare)

Drug & Supplement Interactions

Anticoagulants (may have antiplatelet effects)
NSAIDs (may have additive effects)
Iron supplements (tannins may reduce absorption)

복용 중인 모든 건강기능식품에 대해 반드시 의료 전문가에게 알리십시오.

Related Ingredients

Green Tea Extract Aloe Vera Turmeric (Curcumin) Saw Palmetto

핵심 정보

용량: General: 100-300 mg/day; Skin_Health: 100-400 mg/day standardized to 95% OPCs
제형: capsule tablet liquid extract
천연 원료: Grape seeds, Red wine, Grape skins
상한 섭취량: Generally well-tolerated up to 600 mg/day
권장 복용 시간: With or without food; well absorbed

근거 요약

Aging Skin & Wrinkles C

Hyperpigmentation C

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.