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Borage Oil ： Eczema (Atopic Dermatitis)

C エビデンス 小規模研究からのエビデンスは限られていますが、いくつかの肯定的なシグナルがあります。

Contains 2x more GLA than EPO. Some RCTs showed improved skin barrier function and reduced TEWL in atopic dermatitis. Cochrane review findings are mixed for GLA oils overall.

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            C

        

        

            
結論

            
            
Contains 2x more GLA than EPO. Some RCTs showed improved skin barrier function and reduced TEWL in atopic dermatitis. Cochrane review findings are mixed for GLA oils overall.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Systematic Review
                
                
                
                
            

            
                Dietary supplements for established atopic eczema.
            
            

                
                Dose: None
                
                
                vs: Placebo
                
                
                Outcome: Atopic eczema severity
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: Adults and children with established atopic eczema

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
8

        
研究数

    

    

        
500

        
参加者数

    

    

        
            
            ↔
            
        
        
Mixed

    

    

        C

        
グレード

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Dietary supplements for established atopic eczema.
                        
                        
                            
                                Meta-Analysis
                            
                            
                            
                        
                    

                    

                        The Cochrane database …
                        2012
                        
                        130 件の引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
500-1,000 mg/day

                    

                    
                    

                        
skinhealth:

                        
1,000-2,000 mg/day (providing 200-500 mg GLA)

                    

                    
                

                
                

                    上限量： Not established; generally well-tolerated
                

                
            

            

            
            

                
研究で検討された用量

                

                    

                        
                            

                                用量
                                期間
                                効果
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Neutral
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                推奨摂取タイミング： With meals
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Soft stools
                        
    • 
                        
                        
  • 
                            ⚠
                            Possible hepatotoxicity with PA-containing preparations (use PA-free only)
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (may have antiplatelet effects)
                        
    • 
                        
                        
  • 
                            ●
                            Anticonvulsants (theoretical seizure threshold concern)
                        
    • 
                        
                        
  • 
                            ●
                            Hepatotoxic medications (PA content concern — use PA-free)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： Not established; generally well-tolerated
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Borage Oil help with Eczema (Atopic Dermatitis)?
            
        
        

            Based on 8 studies with 500 participants, there is limited but promising evidence that Borage Oil may support Eczema (Atopic Dermatitis) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Borage Oil should I take for Eczema (Atopic Dermatitis)?
            
        
        

            Studies have used various dosages. A commonly studied range is 500-1,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Borage Oil?
            
        
        

            Reported side effects may include Mild gastrointestinal discomfort, Soft stools, Possible hepatotoxicity with PA-containing preparations (use PA-free only). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Borage Oil and Eczema (Atopic Dermatitis)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 8 peer-reviewed studies with 500 total participants. The overall direction of effect is mixed.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Fiona J Bath-Hextall et al..
      Cochrane Database Syst Rev.
      2012.
      Dietary supplements for established atopic eczema.
      doi:10.1002/14651858.CD005205.pub3
      PubMed
    
    2. 
    
  















    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。