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SkinCited

Lactobacillus rhamnosus

probiotic

Also known as: L. rhamnosus GG, LGG, Lactobacillus GG

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About





            

                
Lactobacillus rhamnosus modulates the gut-skin axis by supporting intestinal barrier integrity, reducing systemic endotoxin translocation, and downregulating pro-inflammatory cytokines. A landmark meta-analysis found prenatal and early-life supplementation with L. rhamnosus GG reduced the risk of atopic dermatitis by approximately 50% in high-risk infants.

            

        

        

        
        
        

            

  
How It Works





            

                
Modulates the gut-skin axis by supporting intestinal barrier integrity, reducing systemic endotoxin translocation, downregulating pro-inflammatory cytokines (IL-4, IL-13), and influencing Th1/Th2 immune balance relevant to atopic dermatitis.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                Condition
                                Grade
                                Studies
                                Participants
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Eczema (Atopic Dermatitis)
                                    
                                
                                
                                    B

                                
                                
                                    20
                                
                                
                                    3500
                                
                                
                                    
                                        View →
                                    
                                
                            

                            
                            

                                
                                    
                                        Acne
                                    
                                
                                
                                    D

                                
                                
                                    3
                                
                                
                                    200
                                
                                
                                    
                                        View →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Mild gas or bloating (temporary, during initial use)
                
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                    Rare infections in severely immunocompromised individuals
                
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Drug & Supplement Interactions





            
    
                
                
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                    Immunosuppressants (theoretical concern — live bacteria)
                
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                    Antibiotics (may reduce probiotic viability — separate by 2+ hours)
                
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                Always inform your healthcare provider about all supplements you take.
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Bifidobacterium lactis
                    
                
                
                
                    Lactobacillus plantarum
                    
                
                
            

        

        
    


    
    












    

        FDA Disclaimer:
        These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.