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Copper Figures

4 figures from peer-reviewed research

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Figure 6
Figure 6 Diagram

Neurological consequences of chronic manganese exposure are summarized, including cognitive impairment, motor dysfunction, and emotional disturbances. The symptoms collectively termed manganism share clinical features with Parkinson's disease.

Consequences of Disturbing Manganese Homeostasis.

Figure 7
Figure 7 Diagram

Manganese's dual role as both essential nutrient and potential toxin is explored through its effects on enzymatic systems. Superoxide dismutase, arginase, and glutamine synthetase all require manganese as a cofactor for normal function.

Consequences of Disturbing Manganese Homeostasis.

Figure 2. Effects of Mn dysregulation.
Figure 8 Diagram

A comprehensive diagram maps the systemic effects of manganese dysregulation across multiple organ systems. Both deficiency and excess disrupt metabolic processes, with the nervous system being particularly vulnerable to manganese imbalance.

Consequences of Disturbing Manganese Homeostasis.

Figure 4. A model of the imbalance in the Mn transport system.
Figure 10 Diagram

A model of manganese transport imbalance depicts the interplay between uptake, distribution, and excretion mechanisms. Disruption of transporters such as SLC30A10 and SLC39A14 can lead to pathological manganese accumulation in target tissues.

Consequences of Disturbing Manganese Homeostasis.