Hyaluronic Acid لـ Dry Skin
B الأدلة تدعم ذلك تجربة عشوائية واحدة على الأقل، مع نتائج متسقة في معظمها.Multiple RCTs found oral hyaluronic acid (120-240 mg/day) significantly improved skin moisture and reduced transepidermal water loss (TEWL) over 4-8 weeks compared to placebo.
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B
الخلاصة
Multiple RCTs found oral hyaluronic acid (120-240 mg/day) significantly improved skin moisture and reduced transepidermal water loss (TEWL) over 4-8 weeks compared to placebo.
Key Study Findings
animal study
A bioactive three-layered skin substitute based on ECM components effectively promotes skin wound healing and …
Dose: three-layered bioactive skin substitute (BT Skin) containing collagen type I, agarose, dermatan sulf
مقابل: Placebo
التأثير: None
None
Other
6 weeks
Controlled Release of Minoxidil through Hydrogel Cross-Linking to Treat Androgenetic Alopecia.
Dose: None
مقابل: Intradermal injection hydrogel in mouse model
Outcome: Anagen induction in mouse model
التأثير: None
None
المجتمع المدروس: Mouse model of hair loss
Other
Application of platelet-rich plasma lysate combined with hyaluronic acid microneedles for the treatment of alopecia.
Dose: None
مقابل: Minoxidil (once/day x20) vs PL-MN (once/3 days x5)
Outcome: Hair follicle anagen induction in mouse model
التأثير: None
None
المجتمع المدروس: Mouse model of alopecia
In Vitro
Engineered Microalgal Extracellular Vesicles for Enhancing Mitochondrial Homeostasis in Radiodermatitis Prevention.
Dose: None
مقابل: None
Outcome: Protection against radiation-induced cellular damage
التأثير: None
None
المجتمع المدروس: In vitro/in vivo radiodermatitis model
Other
Bifunctional sodium hyaluronate microneedle patches integrating 5α-reductase and ROS regulation for boosted hair regeneration.
Dose: None
مقابل: In vitro DPC model and in vivo mouse model
Outcome: DHT inhibition, ROS elimination, hair growth
التأثير: None
None
المجتمع المدروس: Dermal papilla cells and mouse hair growth model
Case report
n=3
Cosmetic filler-induced hair loss: case series and literature review.
Dose: 5% minoxidil topical
مقابل: Placebo
التأثير: None
None
Key Statistics
10
الدراسات
620
المشاركون
↑
Positive
B
التقييم
Referenced Papers
Materials today. Bio
2025
10 اقتباسات
ACS nano
2025
6 اقتباسات
Drug delivery and …
2025
3 اقتباسات
International journal of …
2025
2 اقتباسات
Controlled Release of Minoxidil through Hydrogel Cross-Linking to Treat Androgenetic Alopecia.
Other
ACS biomaterials science …
2025
2 اقتباسات
Regenerative biomaterials
2025
Regenerative biomaterials
2024
18 اقتباسات
The Journal of …
2024
2 اقتباسات
Platelet-Rich Plasma and Genital Rejuvenation.
Case Report
Skinmed
2019
7 اقتباسات
Alternative medicine review …
2003
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- general:
- 120-240 mg/day
- skinhydration:
- 120-200 mg/day
الحد الأعلى: Not established; well-tolerated up to 200 mg/day in trials lasting 12 months
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| three-layered bioactive skin substitute (BT Skin) containing collagen type I, agarose, dermatan sulf | -- | Positive | -- |
| None | 6 weeks | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 5% minoxidil topical | -- | Positive | 3 |
| None | -- | Positive | -- |
| Arginine, glutamine, vitamin C, zinc | -- | Positive | -- |
أفضل وقت للتناول: With meals for better absorption
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ Generally well-tolerated
- ⚠ Rare mild gastrointestinal discomfort
التفاعلات المعروفة
- ● No significant drug interactions documented
الحد الأقصى المسموح به: Not established; well-tolerated up to 200 mg/day in trials lasting 12 months
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does Hyaluronic Acid help with Dry Skin?
Based on 10 studies with 620 participants, there is moderate evidence from clinical studies that Hyaluronic Acid may support Dry Skin management. Our evidence grade is B (Good Evidence).
How much Hyaluronic Acid should I take for Dry Skin?
Studies have used various dosages. A commonly studied range is 120-240 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Hyaluronic Acid?
Reported side effects may include Generally well-tolerated, Rare mild gastrointestinal discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Hyaluronic Acid and Dry Skin?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 620 total participants. The overall direction of effect is positive.
Related Evidence
مكونات أخرى لـ Dry Skin
Hyaluronic Acid لحالات أخرى
References
- [1] Carlos Chocarro-Wrona et al.. Mater Today Bio. 2025. A bioactive three-layered skin substitute based on ECM components effectively promotes skin wound healing and regeneration. doi:10.1016/j.mtbio.2025.101592 PubMed
- [2] Jiarong Cui et al.. ACS Nano. 2025. Engineered Microalgal Extracellular Vesicles for Enhancing Mitochondrial Homeostasis in Radiodermatitis Prevention. doi:10.1021/acsnano.5c07135 PubMed
- [3] Zhengxin Suo et al.. Drug Deliv Transl Res. 2025. Application of platelet-rich plasma lysate combined with hyaluronic acid microneedles for the treatment of alopecia. doi:10.1007/s13346-025-01816-w PubMed
- [4] Yudie Lv et al.. Int J Biol Macromol. 2025. Bifunctional sodium hyaluronate microneedle patches integrating 5α-reductase and ROS regulation for boosted hair regeneration. doi:10.1016/j.ijbiomac.2025.146316 PubMed
- [5] Leo L Wang et al.. ACS Biomater Sci Eng. 2025. Controlled Release of Minoxidil through Hydrogel Cross-Linking to Treat Androgenetic Alopecia. doi:10.1021/acsbiomaterials.5c00292 PubMed
- [6] Tao Ye et al.. Regen Biomater. 2025. Engineered collagen XVII-loaded dissolving microneedle patch for promoting hair regrowth in androgenic alopecia. doi:10.1093/rb/rbaf104 PubMed
- [7] Qin Yang et al.. Regen Biomater. 2024. Dissolvable microneedles loaded ginsenoside Rg3 liposome: a transdermal delivery approach for alopecia treatment. doi:10.1093/rb/rbae086 PubMed
- [8] Yutong Xie et al.. J Dermatolog Treat. 2024. Cosmetic filler-induced hair loss: case series and literature review. doi:10.1080/09546634.2024.2443111 PubMed
- [9] Philip R Cohen et al.. Skinmed. 2019. Platelet-Rich Plasma and Genital Rejuvenation. PubMed
- [10] Douglas MacKay et al.. Altern Med Rev. 2003. Nutritional support for wound healing. PubMed
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