Saw Palmetto
herbAlso known as: Serenoa repens, Sabal serrulatum, Saw Palmetto Berry Extract
About
Saw palmetto inhibits 5-alpha-reductase enzyme, reducing conversion of testosterone to DHT, which stimulates sebaceous gland activity. A small study found saw palmetto reduced sebum production and acne severity in young men. Most clinical data is from prostate health studies.
How It Works
Inhibits 5-alpha-reductase enzyme, reducing conversion of testosterone to dihydrotestosterone (DHT); DHT stimulates sebaceous gland activity, so reduced DHT levels may decrease sebum production and improve hormonal acne; also has anti-inflammatory properties via COX-2 inhibition.
Evidence For Conditions
Side Effects
- Mild gastrointestinal discomfort
- Headache (rare)
- Dizziness (rare)
Drug & Supplement Interactions
- Anticoagulants (may have mild antiplatelet effects)
- Hormonal medications (oral contraceptives, HRT — may interfere)
- Finasteride and dutasteride (additive 5-alpha-reductase inhibition)
Always inform your healthcare provider about all supplements you take.
Related Ingredients
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.