What is the recommended dosage for Aloe Vera?

General: 100-200 mg/day aloe vera gel extract

What are the side effects of Aloe Vera?

Potential side effects include: Diarrhea and cramping (aloe latex — avoid oral latex forms), Electrolyte imbalance (with latex use), Allergic reactions (rare).

What is aloe vera and how may it support skin health?

Aloe vera contains polysaccharides, vitamins, and anti-inflammatory compounds including acemannan. Topical aloe vera is well-established for wound healing and burn treatment. Oral aloe vera gel supplementation has been studied for skin hydration and wrinkle reduction, with some positive findings in clinical trials.

What dosage of oral aloe vera has been studied for skin benefits?

Clinical studies have used 40–120 mg of aloe vera gel powder per day for skin outcomes. A Japanese study found significant improvements in skin elasticity with 40 mcg aloesin (an aloe compound) daily for 8 weeks. Studies on skin hydration and wrinkles used 1,200 mg of aloe gel powder daily for 8 weeks.

What are the potential side effects of oral aloe vera?

Oral aloe vera latex (outer leaf) contains anthraquinones that are potent laxatives and may be carcinogenic with long-term use. Only aloe vera inner gel (decolorized, purified) should be used for supplementation. Aloe may lower blood sugar and interact with diabetes medications. It may also interact with digoxin and diuretics.

Aloe Vera

herb

Also known as: Aloe barbadensis, Aloe barbadensis miller, Aloe Gel, Aloe Latex

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About

Aloe vera gel contains acemannan polysaccharides, anthraquinones, and vitamins that stimulate fibroblast proliferation and support wound healing. Topical use has moderate evidence; oral supplementation for skin is less studied. A small RCT found oral aloe sterol supplementation improved skin elasticity in women over 40.

How It Works

Gel from Aloe barbadensis leaves contains acemannan polysaccharides, anthraquinones, and vitamins that stimulate fibroblast proliferation, support wound healing, modulate inflammatory cytokines, and provide mucilaginous moisture retention.

Evidence For Conditions

Condition	Grade	Studies	Participants
Wound Healing	D	4	200	View →

Side Effects

Diarrhea and cramping (aloe latex — avoid oral latex forms)
Electrolyte imbalance (with latex use)
Allergic reactions (rare)

Drug & Supplement Interactions

Diuretics (additive potassium depletion with aloe latex)
Antidiabetic medications (may lower blood sugar)
Anticoagulants (theoretical interaction)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Grape Seed Extract Green Tea Extract Saw Palmetto Turmeric (Curcumin)

Quick Facts

Dosage: General: 100-200 mg/day aloe vera gel extract
Forms: capsule liquid gel (topical) juice
Natural Sources: Aloe vera plant leaves
Upper Limit: Oral aloe latex: avoid (anthraquinones); gel extracts are generally safe
Best Time: With meals for oral supplements

Evidence Summary

Wound Healing D

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.