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Turmeric (Curcumin) for Psoriasis

C

Curcumin's NF-kB inhibition is relevant to psoriasis pathogenesis. Research suggests oral curcumin (with bioavailability enhancers) may help support skin health in inflammatory conditions.

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The Bottom Line

            
            
Curcumin's NF-kB inhibition is relevant to psoriasis pathogenesis. Research suggests oral curcumin (with bioavailability enhancers) may help support skin health in inflammatory conditions.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
6

        
Studies

    

    

        
350

        
Participants

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Grade

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Commonly Used Dosages

                

                    
                    

                        
general:

                        
500-1,000 mg/day curcumin

                    

                    
                    

                        
skinhealth:

                        
500-1,000 mg/day with piperine or phospholipid formulation

                    

                    
                

                
                

                    Upper limit: Generally well-tolerated up to 8,000 mg/day; 12,000 mg/day tested in trials
                

                
            

            

            

            
            

                Best taken: With meals containing fat and black pepper (piperine increases bioavailability by 2,000%)
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Reported Side Effects

                    
    
                        
                        
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                            ⚠
                            Gastrointestinal discomfort (nausea, diarrhea)
                        
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                            Yellow staining of teeth (powder form)
                        
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                            ⚠
                            May worsen gallbladder conditions
                        
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Known Interactions

                    
    
                        
                        
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                            ●
                            Anticoagulants (may increase bleeding risk)
                        
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                            Antidiabetic medications (may enhance blood sugar lowering)
                        
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                            CYP450 substrates (may inhibit drug metabolism)
                        
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                            Iron supplements (may reduce absorption)
                        
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                        Tolerable upper intake: Generally well-tolerated up to 8,000 mg/day; 12,000 mg/day tested in trials
                    

                

                
            

            

                Always consult your healthcare provider before starting any supplement.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Turmeric (Curcumin) help with Psoriasis?
            
        
        

            Based on 6 studies with 350 participants, there is limited but promising evidence that Turmeric (Curcumin) may support Psoriasis management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Turmeric (Curcumin) should I take for Psoriasis?
            
        
        

            Studies have used various dosages. A commonly studied range is 500-1,000 mg/day curcumin. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Turmeric (Curcumin)?
            
        
        

            Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea), Yellow staining of teeth (powder form), May worsen gallbladder conditions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Turmeric (Curcumin) and Psoriasis?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
Other ingredients for Psoriasis

                    

                        
                        
                            Vitamin D
                            B

                        
                        
                        
                            Omega-3 Fatty Acids
                            D

                        
                        
                    

                

                

                
                

                    
Turmeric (Curcumin) for other conditions

                    

                        
                        
                            Acne
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

        FDA Disclaimer:
        These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.