What is the recommended dosage for Vitamin C?

General: 75-90 mg/day (RDA); Skin Health: 500-1,000 mg/day

What are the side effects of Vitamin C?

Potential side effects include: Gastrointestinal discomfort at high doses (> 2,000 mg/day), Diarrhea, Kidney stones (rare, in predisposed individuals), Iron overload risk in hemochromatosis.

What is vitamin C and how may it support skin health?

Vitamin C (ascorbic acid) is essential for collagen synthesis and serves as a potent antioxidant protecting against UV-induced photodamage. It is also required for melanin regulation. Clinical studies suggest oral vitamin C may support skin barrier function, reduce UV damage when combined with vitamin E, and support wound healing.

What dosage of vitamin C has been studied for skin benefits?

Clinical studies for skin outcomes have used 500–2,000 mg of vitamin C per day, often in combination with vitamin E for photoprotection. The RDA is 75–90 mg. Skin saturation occurs at approximately 200–400 mg daily oral intake. Higher doses are excreted renally. Study durations ranged from 4 to 12 weeks.

What are the potential side effects of vitamin C supplements?

Common side effects at high doses include gastrointestinal distress, diarrhea, and nausea. Doses above 2,000 mg daily may increase risk of kidney stones in susceptible individuals. Vitamin C enhances iron absorption, which may be problematic for individuals with hemochromatosis. The tolerable upper intake level is 2,000 mg daily.

Vitamin C
Vitamin C

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يُعرف أيضاً بـ: Ascorbic Acid, L-Ascorbic Acid, Ascorbate, Ester-C

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About

Vitamin C is an essential cofactor for prolyl and lysyl hydroxylase enzymes required for collagen cross-linking and stabilization. It is also a potent antioxidant that neutralizes UV-generated reactive oxygen species (ROS) in skin. A systematic review demonstrated that higher dietary vitamin C intake is associated with lower risk of dry skin and wrinkles. Deficiency (scurvy) leads to impaired wound healing and skin fragility.

How It Works

Essential cofactor for prolyl and lysyl hydroxylase enzymes required for collagen cross-linking and stabilization; potent antioxidant that neutralizes UV-generated reactive oxygen species (ROS) in skin; supports melanin synthesis regulation and promotes photoprotection.

Evidence For Conditions

الحالة	التقييم	الدراسات	المشاركون
Collagen Loss	A	20	3500	عرض →
Aging Skin & Wrinkles	B	12	2800	عرض →

Side Effects

Gastrointestinal discomfort at high doses (> 2,000 mg/day)
Diarrhea
Kidney stones (rare, in predisposed individuals)
Iron overload risk in hemochromatosis

Drug & Supplement Interactions

May enhance iron absorption (caution in iron overload conditions)
May reduce effectiveness of some chemotherapy agents
May interact with anticoagulants at very high doses

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Related Ingredients

Vitamin E Vitamin A (Retinol) Vitamin D Biotin Niacinamide

حقائق سريعة

الجرعة: General: 75-90 mg/day (RDA); Skin_Health: 500-1,000 mg/day
الأشكال الدوائية: tablet capsule powder chewable effervescent liposomal
المصادر الطبيعية: Citrus fruits, Bell peppers, Kiwi, Strawberries, Broccoli, Brussels sprouts
الحد الأعلى: 2,000 mg/day (IOM Tolerable Upper Intake Level)
أفضل وقت: Can be taken any time; split doses if > 500 mg for better absorption

ملخص الأدلة

Collagen Loss A

Aging Skin & Wrinkles B

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